Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID28876	Olaparib	GSE70138	NEU	Human	24h	0.04uM	EID0121

Response Information :

Types	Number	Response transcription factors
Up-regulation	146	HCFC2; KLF2; SMAD3; ZFPM2; ING1; PEX2; MLLT10; HOXA5; ZBTB25; POU2F2; HOXA4; FOS; HMBOX1; ZBTB20; IKZF5; IRF5; NR0B2; HHEX; ZHX3; RBBP8; CEBPD; BNC2; SUB1; CUX1; NR2C1; SIM1; ZNF8; ZSCAN2; PRDM5; TRIM32; EMX2; YEATS4; ZNF589; SOHLH2; ETV1; HOXC5; TTF1; NEUROD1; ESRRA; LDB1; ZNF552; MLXIPL; PLAG1; TEAD1; HOXC11; PIAS2; ZIC3; IRF8; TADA3; ARNTL; STAT1; IRF9; SP140L; MDM2; MEF2A; ASCL1; ZNF671; RBL2; IRF6; MED27; MYOG; JAK2; TSC22D4; POU5F1B; HMGB2; TLX1; NR1I3; ZKSCAN3; CCNC; TCF15; ZNF587; EGR1; LMCD1; DDIT3; MXD4; MNDA; MED14; ERBB4; SMARCA1; KLF9; PITX3; IL16; GTF3A; MAFG; MECP2; PIR; APBB1; STAT6; KLF7; ZNF586; GATA6; WHSC1L1; SP100; DBP; ZNF107; HOXA1; HOXA3; HOXC4; INSR; ZNF536; MYBL2; CNOT2; CREB3L2; MITF; ZNF771; ZNF136; CLOCK; CREG1; ZNF222; HOXC8; ZNF134; DNMT3B; ACTL6A; SMAD4; NFIB; PAX6; BARX1; SOX10; TFEB; RUVBL1; HTATIP2; ANKRD1; CBFB; ABL1; MTDH; ATF7IP; SOX17; SMAD7; RORA; LOXL2; MNAT1; SOX9; HMGA1; LITAF; CHD7; HMGN3; ID2; MEF2C; DMTF1; MYRF; NR4A1; CITED2; HOXB2; ADRB2; SSBP2; NFATC3
Down-regulation	201	HIC2; TCF25; SMARCA5; HOXB13; BRD2; PITX2; PHF20; KMT5A; BRD7; BHLHE41; PPRC1; TULP3; MED21; GTF2F1; PQBP1; ZNF672; ZNF768; CHD8; ZNF140; NCOA1; MAZ; SUPT7L; TAF9B; MYT1L; ZEB1; RYBP; CENPF; MXI1; BRD8; PRMT2; PSPC1; CTCF; TRIM29; TOX4; ERF; ZNF148; EYA1; SP3; HOXD11; BCL11B; CBFA2T2; MAPK8IP1; SHOX2; BAZ1A; GLI2; RUNX3; USP21; CAMTA1; SMARCB1; NKX3-1; CTNNB1; ZNF665; ADNP; RAN; BIRC2; HIRA; ZNF467; FOXF2; SMARCC1; PATZ1; GTF2I; ZNF12; PKNOX1; UBE2L3; TBX3; ZNF146; ILF2; MED13; NKX2-2; CHD1; TOX3; HIVEP2; YBX3; ZNF529; BACH2; REST; ZHX2; CDK2; TGIF2; TCERG1; POU4F1; NUP62; ZNF177; TCF20; TLE4; BBX; MED1; NFYC; APEX1; BTG1; GFI1; UBE3A; ZNF267; TRIM28; ZNF32; ZNF430; MEIS2; MKL2; VEZF1; EGR4; ARID5B; MTF2; HSBP1; ZNF573; EGR3; MAFB; TRPS1; CREBL2; TBX2; NFIL3; NCOA4; HIVEP1; SMARCA4; RNF111; HDAC2; UBE2I; ZNF432; HIPK1; ZBED4; CDK8; MED6; ZEB2; PBRM1; NR4A3; PSMC3; TDRD3; TCF7L2; SMARCC2; PCGF2; BASP1; RLF; SOX11; TSC22D3; BCLAF1; SPEN; BCOR; SFPQ; HOXC10; BCL11A; MYCN; RBM39; SMARCE1; KLF5; RARA; KLF10; TSC22D2; SCAND1; MED23; HDAC6; ZIC1; MYCBP; ID1; NONO; DACH1; EZH2; TBL1X; EN1; ZNF512B; SERTAD2; NR2F2; DLX2; MED24; EGR2; PEG3; TERF2; ID4; SAP18; HMGB3; EPAS1; DAXX; CARHSP1; CUX2; ID3; IRF1; ARID4B; REL; SMARCD3; RBPMS; CRK; TFAP2C; ZNF331; TCEB2; KLF4; PSIP1; NCOR2; EHF; PFDN5; ERG; ELF3; LEF1; FOXG1; TSC22D1; NRIP1; HEY1; MYBL1; MSX1; RBBP4; POU2AF1; TCF4; NR3C1; HES1