Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID28874	Olaparib	GSE70138	NEU	Human	24h	0.37uM	EID0121

Response Information :

Types	Number	Response transcription factors
Up-regulation	140	FHL2; REXO4; NPAS2; CIZ1; GATA4; HOXA5; SIN3B; GFI1B; UTF1; ETV2; BNC2; DPF2; ZNF589; FOS; CREB3L2; HOXA4; HHEX; NANOG; JUNB; LHX5; ARHGAP35; MNDA; TTF1; ETV1; MYB; HOXA2; NFE2; RUVBL1; SUB1; POU5F1B; ING1; SOX13; MDM2; SCRT1; RSF1; ESRRA; TEAD4; KDM2A; IKZF1; ADNP2; MTDH; NR1I3; PPARGC1A; SP140L; HOXA7; HLF; MTA2; CUX1; ETV5; KLF1; SSX7; SMAD1; ZNF593; PIAS3; TRIP6; HIPK2; JAK2; MEF2A; SSX1; KLF15; ARID3A; TLX3; PTRF; DNMT3B; MLLT10; PIR; MYBL2; GATA1; VSX1; HOXA6; NR0B2; MBD2; AIRE; ETV4; ZNF282; WWC1; RBBP8; TCF3; KMT2D; LYL1; CBX3; BMI1; LDB1; TRIM24; CITED2; MEF2C; CRK; ATF6; PREB; ZHX3; FOXL2; MYRF; ZNF33B; TGFB1I1; MLXIP; EGR1; BARX1; HMGB2; CEBPB; LIN28A; PGR; FOSB; NFATC4; ANKRD1; SOX10; NR5A2; FOXE1; DBP; GATA6; BHLHE41; IFI16; POU2AF1; ZFP36L2; NFIC; FOXA1; ZFPM2; SATB2; NFE2L3; NR1H2; SALL1; LITAF; TRIM22; KLF2; ZNF211; YWHAB; HTATIP2; PLAG1; HOXD1; PSIP1; GATA2; YBX3; FOXA2; DMTF1; IL16; GATA3; HMGN3; PBX3; SOX17; CD3D; SSBP2
Down-regulation	164	ZBED1; MAML1; SOX11; MXI1; NR4A3; RBPJ; BAZ1A; BTG1; BBX; RNF6; ZSCAN16; MXD3; NCOA4; DEK; CDK8; INSM1; TCF4; DDX17; DACH1; EZH2; RAN; MTF2; GTF2I; TDP2; BCL11A; MAZ; KAT8; ZNF184; CDK2; MEIS2; NEUROD1; ZEB1; SMARCC2; HOXB13; SUMO1; SAP18; MKL1; ZNF148; CHD3; ZNF143; CTBP2; MSX1; HMGB3; BRD7; CERS4; VDR; VEZF1; ING4; RCOR1; EGR2; TFCP2; PBRM1; FOXO1; ORC2; PLAGL1; SIX3; MEOX1; UBE2I; TLE4; NFIL3; PAX6; PKNOX1; SPIB; BATF3; CNOT6; CENPF; BAZ2B; PCGF3; THAP4; TTF2; NONO; HOXC4; EN1; PSPC1; ZNF189; BPTF; TSC22D2; CREM; CCNT1; BACH2; BRD8; ZNF350; CARHSP1; BCOR; NFYB; NUP62; MED1; GTF3A; CAMTA1; MED13; ZNF165; NKX2-2; TWIST1; PHF20; PAX5; SIAH2; ZMYM2; BTF3; TAF7; HDAC6; ERF; ZNF430; TCERG1; ZNF529; EYA1; MED23; TBX2; SMARCE1; BRD2; CALR; FOXG1; HOXC10; SMARCA4; DAXX; ZNF43; PURA; REL; STAT6; SMARCC1; MEOX2; ZFHX4; MYT1L; TULP3; E2F5; TOX3; ZNF117; CDYL; TSC22D1; TGIF1; TCF12; HSBP1; MYCL; SIX1; HIC2; ZNF146; YBX1; ARID5B; PMS1; PSMC3; E2F3; KLF5; PCGF2; HDAC2; PFDN5; KDM5D; NFATC3; FOXF2; EHF; IRF8; ARID4B; ID4; MNAT1; FOXJ3; BCL6; MED24; MKL2; LEF1; RBBP4; BASP1; NRIP1; PEG3; ZNF586; NR3C1; RELB