Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID28871	Olaparib	GSE70138	NEU	Human	24h	10uM	EID0121

Response Information :

Types	Number	Response transcription factors
Up-regulation	135	EED; TBP; ZEB1; SOX2; CTR9; PCGF2; FOXO4; SMAD3; CREBZF; TBL1X; SAP30; BRD4; NPAT; ZIC1; TAF1D; RERE; NLK; KDM5D; ZNF711; KLF2; BMI1; EGR3; EGR2; SMAD2; RORA; ZBTB1; KMT2A; HDAC4; PKNOX1; ZNF629; BPTF; PEX2; RHOA; EDF1; SCAND1; CHD4; MAFB; SMARCD3; BIRC2; DPF2; TSG101; POU2F1; ZNF292; NCOR2; YBX1; RBM14; PBX1; HDAC6; BRD3; NONO; TBPL1; TAF10; RBPJ; MED17; IRF2; CHD7; ARID4A; SMARCA4; ZKSCAN7; FOXO3; BAZ2B; TRIM32; KAT2B; TOX3; IRF4; PUF60; ZNF532; SP110; NUP62; COPS2; MED23; PMS1; FOXO1; MAX; ARID4B; MAGED1; TLE4; NCOA1; MYCN; RCOR1; NR2F1; NCOA4; MED1; HDAC1; RBBP4; NFYC; RAN; ZMYM2; ARID1A; HDAC2; CBX6; SSBP2; TLE1; PDLIM1; YAP1; MYT1L; POU2AF1; RFX5; ZMYND8; TCF12; UBE2I; GTF2IRD1; CREB1; BRD2; BASP1; MTF2; MNT; DDX17; HOXB6; ZFHX4; FOXJ3; KLF9; CHD9; RLF; EYA1; TOB1; ID4; DACH1; VGLL4; SUB1; MEIS1; PAX5; TCEB2; SMAD1; BTG1; HLTF; SIX1; SPEN; NR2F2; CEBPB; ZMIZ1; MAF; HMG20B; ASCL1; ID1
Down-regulation	198	CDK2; CTNNB1; ZKSCAN4; ARNT2; NRIP1; CNOT3; ZNF74; BRDT; CALR; ZFP69B; YEATS4; ZNF665; PEX14; PSMC3IP; ZSCAN16; ZNF749; AEBP1; POLR3C; ZNF552; ZNF551; ZNF350; BRCA2; ZNF557; ZNF165; CNOT1; ZNF813; MTA2; SCAI; ZNF304; TEF; ZNF493; BARX2; LIN28A; TBX5; TRIB3; GATA4; SIX5; MAK; MYCL; NR1H4; TERF1; IRX4; SLC2A4RG; HOXD1; ZFX; ZNF426; WDR77; IRF6; SOX10; ACTL6A; TAF6L; MNX1; E2F4; ZNF671; MLXIP; MYBL1; SOX14; MBD4; SSX7; HOXA4; TBX1; ZNF816; TAF4B; FOXL1; TTF2; ZNF652; FOXM1; SUPT3H; ZNF253; BRIP1; ZNF134; ZBTB7B; ETS1; AFF4; ZNF224; SPDEF; GFI1B; YBX3; HESX1; ZNF222; KDM5C; ZNF345; OVOL2; FOXC1; ZNF394; VGLL1; TGIF1; NFATC4; NR0B1; HIVEP1; ZNF669; ELF4; RUNX1; NFKB2; NR1H2; JUNB; TULP2; YBX2; NKX3-1; NFKB1; CEBPG; NKX2-2; JUP; ZNF623; CEBPD; AIRE; NFE2L2; PBX2; ZNF419; SOX18; PSMC3; SRCAP; HOXD3; RUVBL1; TEAD4; ZNF468; ZNF507; BLZF1; CDK9; BNC2; HOXC4; IRF1; NR4A3; FOXA1; ZNF667; ZNF93; PTTG1; FOXI1; DLX2; ZFP36L2; SOX17; HOXB13; TLE2; NKX2-1; PAX6; FOXJ1; BCL11A; TGFB1; TFAP2A; ZNF529; TOPORS; EPAS1; REL; SNAI2; ZNF117; STAT6; WWC1; ZNF107; GATA6; KLF6; TRPS1; E2F8; ATF5; NR0B2; PGR; CD3D; TSC22D2; BARX1; MYBL2; BHLHE41; WWP1; TFDP2; MITF; CBFB; MAFF; TXNIP; RAD21; ERBB4; ZNF331; FLNA; HLX; EGR1; PITX1; ELF3; TRIM29; SPIB; DLX5; EHF; RBPMS; FOS; HOXA5; POU4F1; TP63; ARID5B; HHEX; ATF3; NFATC3; GATA3; PBX3; DAXX; WT1; HES1; SOX9; NR3C1; ZNF586; PSIP1; E2F2; RELB