Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID28861	Tie2-kinase-inhibitor	GSE70138	NEU	Human	24h	1.11uM	EID0121

Response Information :

Types	Number	Response transcription factors
Up-regulation	159	HMGA2; FOXO4; SMARCA5; BAZ2B; ZNF292; EGR3; MAML1; SP3; CHD3; RHOA; CNOT6; TBPL1; ZMYND11; PCGF2; NCOA6; MED7; SCAND1; BCL10; MAGED1; ID4; DDX5; GLI2; ZKSCAN7; ZNF148; DPF2; NFAT5; KMT2A; BBX; EGR2; YWHAB; CHD9; MED1; HSF2; EZH2; SMAD5; ARID4A; EDF1; SALL2; SHOX2; MAFB; FOXD1; ZBTB1; RBBP7; SMAD1; ING2; HDAC6; HDAC2; HAND1; TCERG1; CBX6; UBP1; ZNF24; BRD8; ZNF711; HMG20A; ADNP; CBX5; NFIL3; PKNOX1; CITED2; CARHSP1; BCL11B; HLTF; NUP62; PHF20; KAT6A; ID2; ZSCAN18; SMARCD3; HEY2; RBFOX2; RLF; SAP30; TSC22D3; TBL1X; PUF60; TSC22D2; KDM5D; FUBP1; NLK; ZEB2; PDLIM1; HMGB3; ASCL1; HMGN3; RUNX3; JUND; NCOR2; MECP2; ARID4B; TLE4; NFYC; PIAS1; ZNF302; RBBP4; SMARCC1; MTF2; PLAGL1; ZNF654; DDX17; ENO1; SMARCA4; TBL1XR1; MED13; RYBP; MLXIP; TCEB2; CTBP2; MED23; BCLAF1; PEG3; BMI1; ZIC1; ZNF217; MYT1L; ZNF131; NFIB; IRF4; PLAGL2; LEF1; ST18; ZFHX4; ATF7IP; INSM1; CTR9; ZMYM2; BCOR; FLNA; VGLL4; RCOR1; UBE2I; ABL1; RORA; SSBP2; NAB1; VEZF1; DMTF1; POU2AF1; HOXC6; ZMYND8; FOXJ3; MYCN; ATF4; FOXG1; NRIP1; JARID2; STAT4; SPEN; EYA1; TOB1; ETS2; HMG20B; MYB; WT1; TOX3; TSC22D1; SATB2; ZBTB18; NFATC3
Down-regulation	162	TCEA1; TRIB3; KLF1; CDK2; TAL1; ZNF394; SP140L; YBX3; ZNF74; TAF6L; LOXL2; IRF3; CNOT3; ZNF154; TBX5; HNF4A; HOXA3; TP63; HOXA4; CEBPG; SLC2A4RG; CCNH; SRF; VAX2; ZEB1; ATOH1; TGS1; ZNF215; ZNF44; RBPJL; TAF11; KDM4C; FOXM1; KLF11; YEATS4; SPIB; TGFB1I1; IRF6; CBFA2T3; ALX4; THAP10; ZBTB48; LITAF; MECOM; CALR; PEX2; CEBPE; CREBL2; PROP1; FOXI1; TRIM22; PA2G4; HOXD11; OVOL1; POLR3C; SKIL; MEIS2; STAT6; REL; TFCP2L1; EMX1; MNDA; SP100; NR1H2; ZNF512B; JAK2; NR0B1; GCFC2; ELK3; GFI1B; E2F8; ZBTB16; SIM2; SNAPC4; CSDC2; FOXJ2; GATA1; ZNF264; HSF1; KDM5C; ZNF224; SRCAP; SIX6; ZNF136; BTG1; TP73; SPDEF; RUVBL2; RBBP8; THAP7; ZNF652; FOXF2; TEAD4; NR2F6; CEBPD; TRIM29; SATB1; KLF5; AEBP1; GATA6; SP140; BCL11A; MYBL2; ZNF232; CD3D; NFE2; JUN; SMARCA2; ASH2L; ZNF107; WWP1; FOXA2; ID1; MYCL; PSMC3; ZNF239; TRIM16; KLF9; OSR2; MEF2A; TFAP2A; TULP3; HOXA5; PTTG1; CREB3L1; TCF7; NFE2L3; PAX6; NR5A2; IRF1; FOXN3; JUNB; KLF4; HMGA1; ZNF160; RUNX1; EMX2; ERBB4; MYBL1; ZNF331; PRRX1; BCL3; ESR1; ARID5B; ZFP36L2; BCL6; EPAS1; ATF3; IFI16; NR2F1; SOX17; GATA3; KLF6; ADRB2; DAXX; NR3C1; HES1; PITX1; PSIP1; E2F2; RELB; ZNF586