Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID28834	Regorafenib	GSE70138	NEU	Human	24h	0.04uM	EID0121

Response Information :

Types	Number	Response transcription factors
Up-regulation	91	BNC2; MEN1; CTR9; TAF10; BATF3; TCF25; GLI1; FOXK2; IRF4; CERS4; KDM4C; SUB1; RRN3; CCNC; RBPMS; OSR2; MYCL; HTATIP2; TFCP2L1; FUBP1; STAT5A; FOXH1; ZHX2; MED24; SMARCA2; CERS6; HOXD1; ING3; SALL2; ITGB3BP; BCL11B; ZMIZ2; NR3C2; ZNF430; TP63; TXNIP; MYOG; SND1; BHLHE41; ZBTB20; ESR1; FOXL2; SF1; POU5F1B; MED17; ZNF593; JAK2; KLF9; IRX4; ZNF423; PSIP1; PIAS1; PHF8; HDAC4; HLF; ID2; ZNF589; NANOG; MAFF; CREB3L2; CITED1; TCF7L2; KMT2A; RBBP8; SMARCD3; KAT7; ASCL1; NR5A2; TOX3; SMARCA1; HOXA11; MED13; TRIM22; UBE2I; ZFPM2; TCERG1; PDLIM1; CD3D; SSX1; MKL2; POU4F1; ARID4B; NFE2L3; EGR3; NFATC3; CITED2; NFIB; DNMT3B; INSR; HMGN3; EMX2
Down-regulation	133	ZNF112; USP21; MED21; CENPF; ZSCAN9; FOSB; CENPB; NCOA3; TAF9; MEIS1; ZNF222; HDGF; E2F6; NR2F6; DR1; SOX12; SUPT7L; ARID3A; ZFHX3; VGLL4; DLX2; MBD4; ZNF133; SOHLH2; ZBED4; IRF3; ZNF227; CALR; TGFB1; C1D; SMAD7; ZNF410; PCGF1; CALCOCO1; FOXJ2; FOXA1; TFAP2A; BACH1; ZNF235; ZNF254; ENO1; TEAD3; NRBF2; MAF; ZNF573; DDX17; ZNF415; FOXF1; CNOT3; ZNF232; SMAD4; SPI1; TCF7L1; NCOA6; TLE4; ZNF302; FOXM1; RUVBL1; BCL11A; RCOR3; PLAGL2; TAF9B; ZNF84; ZNF350; EN1; YBX1; SAP30; AEBP1; NONO; GTF2I; LMCD1; TRPS1; CBFB; RUVBL2; PBX1; TSC22D1; IRF8; EYA1; ELF1; ZSCAN18; ZNF654; HOXC10; FOXJ1; PURA; NFE2L2; ID3; BTF3; ELF4; SPEN; PAX6; ETS2; LITAF; PLAG1; ELF5; NKX3-1; ZNF652; ISL1; RUNX1; FOXN3; MYBL1; TULP3; BCL6; ADNP; LOXL2; ZNF146; PHF20; ZNF131; NCOR2; TCF4; PTRF; YWHAB; TRIB3; ZFP36L2; FOSL2; FOXG1; HHEX; ELK3; KLF4; GTF3A; MSX1; HEY1; DACH1; SMAD1; FOXJ3; SOX9; ID1; MNAT1; DAXX; NR3C1; BASP1; ZNF586; HES1; RELB