Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID28830	Regorafenib	GSE70138	NEU	Human	24h	3.33uM	EID0121

Response Information :

Types	Number	Response transcription factors
Up-regulation	124	IKZF1; TERF1; ZBTB16; SAFB; USP16; SMARCB1; PCGF2; PRMT2; TOX3; MEN1; SMARCD1; EHMT2; CTCF; UBE2L3; DEK; BBX; ZNF672; TBL1XR1; MYBL1; AATF; ZZZ3; NPAT; CHD3; RFX7; LHX1; KDM4C; PKNOX2; PBX1; CITED2; ZBTB24; SMARCC2; CREM; FOXK2; MYCL; MED1; ARNTL; ENY2; HIC2; HOXB7; ING2; KLF9; TRAK1; ZHX2; MAZ; DNAJC1; BACH2; JARID2; SREBF2; NCOA2; SIRT7; ZNF219; RBM14; ZNF24; ZNF536; BIRC2; ID1; SMAD2; ASH2L; SMARCE1; KAT8; PAXBP1; MYCN; PSPC1; ZNF148; JUND; LIN28A; ING3; COPS5; ZNF423; URI1; ZNF589; SAP18; BMI1; RNF138; BRD4; RYBP; EDF1; GATA1; LEF1; SSX1; PIAS2; PSIP1; DDX17; HNRNPD; EPAS1; NFATC3; HLTF; PAX5; POU4F1; BHLHE41; BCL11B; PDLIM1; ID3; ERBB2; ID4; MKL2; TXNIP; MEOX1; SMARCA4; ID2; NONO; CERS6; TGIF1; RBBP4; MYT1L; ZNF91; CARHSP1; YWHAB; FOXJ3; SOX13; CHD7; EMX2; FOXD1; TBX3; NR4A1; ARID4B; TSC22D1; TOB1; SPEN; HOXB2; MAGED1; HMG20B; ZMYM2; WT1
Down-regulation	103	TRIB3; ISL1; IFI16; ESRRG; LITAF; IRF6; ARNTL2; MED14; HIPK1; YBX3; BATF3; OSR2; SP100; HLX; NR1H3; ZFX; ZNF350; FOXI1; NRBF2; PHOX2B; HHEX; ESR1; CNOT2; C1D; SIAH2; AR; RUNX1; IRX4; RBPMS; TCF7L2; ZEB1; SP140L; ELF1; FOXE1; PCGF1; TGFB1I1; ZNF512B; PIR; SP3; ZKSCAN1; KLF7; ERG; PREB; SUB1; ETS1; GRHL2; VGLL4; PPP1R13L; TRIP6; TFEC; NFE2L2; TFAP2C; IRF7; TBL1X; IRF9; SHOX2; LOXL2; LPIN2; NR1H2; ZNF83; SIX2; WWTR1; ELF3; ZNF217; ZBTB43; TRIM16; EGR2; MNDA; NKX2-1; DLX2; REL; NAB1; RAD21; TP63; CREB3L1; FOXF1; TWIST1; MEIS1; TRPS1; MSX1; NKX3-1; SERTAD2; HEY1; BCL3; ASCL1; IRF8; FOS; EHF; MYB; ETV1; POU2AF1; AHR; NR3C1; TLE4; PEG3; PBX3; DACH1; SSBP2; ZNF586; ZBTB18; RELB; HES1; E2F2