Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID28786	Alectinib	GSE70138	NEU	Human	24h	0.37uM	EID0121

Response Information :

Types	Number	Response transcription factors
Up-regulation	50	ZNF589; SMARCB1; ZBED1; BCL11A; ZEB1; PAX6; CDK2; MED21; ATN1; SREBF2; HMGB1; PMS1; NFIB; NR2E1; CBX5; ZNF580; TCEA1; TOB1; ITGB3BP; PSMD9; NFIC; SLC2A4RG; TGFB1I1; SHOX2; HMGA1; HTATIP2; PSIP1; ZBTB16; FOXM1; CDK8; KDM5D; ATF5; BRD4; ESR1; SUB1; PFDN5; AEBP1; ATF3; JUN; ZSCAN18; LEF1; YBX3; CEBPB; DACH1; PAX5; ZIC1; HOXB6; SOX9; SATB2; BASP1
Down-regulation	83	ZNF160; CRK; ZNF611; ZNF665; NR1D2; NR3C2; ZNF721; MED6; MNT; SUZ12; HMBOX1; ZNF652; EGR4; IFI16; MTF2; ZNF44; TEAD1; SMAD6; NR1H4; TBL1X; BCL10; SIX3; TCF7; SIX1; C1D; EGR2; ZNF189; ZNF91; GFI1; STAT2; NKX2-2; ADNP; ZNF304; BBX; MAGED1; ZNF224; ZEB2; ZNF512B; NPM1; BTF3; ZNF32; WNT4; ING3; SKI; ELF3; ZNF117; ZNF430; NKX3-1; AFF1; ID1; CTBP2; HDAC1; TOX3; PLAG1; FOXF1; MITF; LITAF; ZNF264; ZMYND8; PURA; MAF; NFAT5; SMAD7; TFEC; KLF10; ZFHX4; TXNIP; YWHAB; TOX; PEG3; AHR; EPAS1; NFATC3; NR2F1; FOXJ3; TLE4; KLF4; BCL3; GATA6; NR2F2; TBX3; NR3C1; RELB