Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID28783	Alectinib	GSE70138	NEU	Human	24h	10uM	EID0121

Response Information :

Types	Number	Response transcription factors
Up-regulation	123	ZBTB32; CIITA; HIPK1; NOC2L; ZSCAN5A; MEF2C; PRMT2; ARRB1; TCF25; ZZZ3; ZNF768; MYCL; GCFC2; TAF1C; USP16; HIRA; SOX9; OLIG2; TAF6L; ZNF444; ZNF589; JAK2; TGIF2; ZNF423; CDX2; FLI1; RXRA; HIC2; CEBPD; MAX; TRIM22; BRD2; TAL1; EPAS1; THRA; ZBTB7B; ZBTB48; ZNF227; CNOT1; CNOT3; UBE2L3; CEBPE; TFCP2; ZHX2; ARL2BP; MYB; TCF7L2; ZEB1; TOX3; PTRF; RNF141; NAB2; BHLHE41; KLF9; PML; CSDE1; FOXJ2; CDK9; ASH2L; TRAK1; CBX7; HIPK3; PIR; STAT1; MNDA; BRWD1; BLM; ZNF189; CERS6; CBX6; FOXE1; SMARCA2; MED1; BACH2; MED24; CENPB; TFAM; IRF8; ELK4; NR2F1; FOXC1; TRIM16; PSPC1; PMS1; ASCL1; FLNA; E2F8; RCOR1; PCGF2; TERF2; TXNIP; DAXX; JUN; ERF; ERG; HLF; PSIP1; HDAC4; ERBB4; ESR1; PAX5; ZSCAN31; SAP30; KLF4; BTG1; PRRX1; MYCN; HHEX; AEBP1; THAP11; FOXA2; OSR2; PBX1; POU4F1; NFE2L3; YBX3; MECOM; SOX17; NFATC3; TSC22D1; SATB2; TCF4; WT1
Down-regulation	94	ZMIZ1; MED21; C1QBP; ESRRG; LITAF; CAMTA1; TAF7; HMG20B; ELK3; SMAD7; NCOR1; MEOX2; HMBOX1; ZNF44; NR2C1; GON4L; VGLL4; HAND1; ZNF43; HOXB2; SIAH2; SOHLH2; TSC22D2; ZNF611; HOXB6; NRBF2; MNT; FOXA1; AIP; AES; RAN; ZNF281; GTF3A; KMT2A; ZNF721; ZNF160; PMF1; ZNF22; MTDH; CREB3L2; URI1; DNMT3B; XBP1; HOXB5; BCOR; DBP; GTF2IRD1; DDIT3; DLX2; RYBP; ELF4; DNAJC1; SMAD1; INSR; MLXIP; ZNF146; TBL1X; SMAD6; SIX2; YBX1; INSM1; SREBF1; PFDN5; RORA; ELF5; TLE4; ISL1; RLF; PLAGL1; EYA2; PQBP1; SIX1; CREB5; TGFB1I1; ZNF91; IRX5; MEIS1; HOXD1; HMGN3; TRIP6; NKX3-1; BMI1; TCEB2; PBX3; ZNF217; SMARCD3; ID4; NR2F2; RUNX3; LMCD1; SUV39H1; NR3C1; HES1; RELB