Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID28758	Dabrafenib	GSE70138	NEU	Human	24h	0.12uM	EID0121

Response Information :

Types	Number	Response transcription factors
Up-regulation	73	PRMT2; CAMTA1; HIRA; PAXBP1; PAX6; DEK; ZHX2; ZNF430; FLNA; RBBP4; ZNF423; HIVEP1; KLF9; ZEB2; CBX5; MNDA; CTBP2; PKNOX1; ISL1; NKX3-1; KDM4C; PBX1; BHLHE41; TRIM29; POU2AF1; TCF7; OLIG2; TFEB; BBX; HOXB13; YBX1; TERF2; DDX17; SMAD1; SOX9; MED1; ABL1; BCLAF1; HEY2; SMAD2; KLF2; CERS6; PCGF2; PSIP1; INSR; CBFB; DMTF1; JUP; BRD2; ERBB2; ZNF302; ERBB4; SAP30; NR2F1; ARID5B; SUB1; MYB; ATF4; TSC22D1; CREB5; PITX1; ATF3; ZFP36L2; ETS2; FOXJ3; TOX3; POU4F1; GATA6; TXNIP; KLF4; KDM5D; SSBP2; BASP1
Down-regulation	52	ZNF45; ZNF444; ZNF516; PIAS3; CITED2; YEATS4; EGR4; REST; TFCP2L1; ZNF304; HOXB2; GFI1; ESR1; BNC2; WWTR1; LPIN2; MDM2; HOXB5; DLX5; FOSB; SP100; ELF4; DDIT3; CCNE1; ZFP36L1; DBP; ZNF134; PLAGL1; HOXA11; RUNX3; TBL1X; FOXO1; ZBTB16; LOXL2; HLX; MITF; NFE2L2; AHR; BCL3; MSX1; DLX2; TRIP6; SOX17; NFATC3; FOSL2; RBL2; GATA2; IFI16; EMX2; DAXX; RELB; NR3C1