Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID28756	Dabrafenib	GSE70138	NEU	Human	24h	1.11uM	EID0121

Response Information :

Types	Number	Response transcription factors
Up-regulation	73	ZBTB39; CREB3L2; TRIM29; SIM2; PCGF1; ARID1A; ATF4; HOXC6; ADRB2; SND1; ZNF24; RYBP; ZNF267; SIX2; BATF3; JARID2; RRN3; KLF7; MED1; NCOA1; GATAD2A; ETV5; PCGF2; PREB; CHD8; BBX; KDM2A; HSF2; NEDD8; TCF20; HDAC4; CBX5; MED13; BCL11B; HTATIP2; HMBOX1; ZEB1; RORA; NFATC3; FOXD1; CTBP2; NKX3-1; SMARCA4; PSIP1; CERS6; KLF5; DMTF1; SOX9; FOXC1; ZNF146; ZBTB43; SMAD1; ERG; MYCN; ZEB2; ARID4B; FOXJ3; CREB5; MKL2; TBX3; MYRF; NFIB; STAT4; RUNX3; SSBP2; JUP; SPEN; ZMIZ1; HEY1; HMG20B; ZMYM2; MSX1; TLE1
Down-regulation	99	ZSCAN16; KLF1; ZNF223; CREBL2; ZBED1; BANP; ZNF573; TAL1; FOXI1; ZNF665; AES; ZNF345; TFCP2L1; ZNF75D; ZFP36L1; NFX1; HOXD11; ZNF623; SNAPC4; NKX2-2; CALR; HSF1; RBL2; LPIN2; GATA1; ZNF239; ZNF415; CNOT3; SPI1; NEUROD1; ZNF606; ZNF165; TXNIP; IFI16; CBFA2T3; HOXB2; WT1; OVOL2; NFE2; MYB; PNRC1; FOXN2; MDM4; ZNF217; ZNF580; YBX1; MEIS1; NR1H3; ATF3; KLF2; BHLHE41; TLE2; ESR1; AR; EMX2; EHF; WWP1; SP110; ZNF264; ELF4; DLX2; ZNF544; RBBP8; ZSCAN18; FOXJ1; PAX5; CITED2; SKI; PLAG1; RBPMS; ZNF329; KLF4; SPIB; MNDA; CREB3; LOXL2; TRIP6; YBX3; GATA2; MECOM; ZFPM2; IRX5; HOXD1; TGFB1I1; MAF; PRRX1; ETS2; AEBP1; TGFB1; SOX17; DAXX; LEF1; TCF4; ID1; E2F2; NR3C1; HES1; RELB; ZNF586