Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID28755	Dabrafenib	GSE70138	NEU	Human	24h	3.33uM	EID0121

Response Information :

Types	Number	Response transcription factors
Up-regulation	65	SMAD2; ING3; SHOX2; MED1; TCF7L2; BAZ2A; SMAD1; SMAD4; TFCP2; CNOT1; NR1D2; SIX1; AFF1; NFYC; MAZ; TGFB1I1; TCF7L1; STAT1; PSIP1; CARHSP1; IKBKAP; NKX2-1; ATF4; CREB3L1; CLOCK; MKL2; XBP1; CTBP1; TOX; CITED1; WWTR1; ELF5; RNF138; CRYM; PDLIM1; BCL11B; TCF12; TRIM22; BRD2; BCLAF1; FOXC1; ASCL1; NR4A2; HMGB2; NFATC3; MXI1; PCGF2; KDM5D; SUB1; MEOX2; CITED2; TWIST1; HLTF; NKX3-1; FLNA; MAGED1; ABL1; MECOM; INSR; FOXJ3; ID4; TOX3; BMI1; SATB2; HMG20B
Down-regulation	59	PUF60; TRIB3; EP300; CBX3; HIPK2; PAWR; HOXB5; HOXB6; ELF1; SPEN; HHEX; RBL2; MYRF; ZNF165; TRIP6; SNAPC4; HOXB2; ELK3; FOXN2; MITF; ZHX3; EN2; RCOR3; ETS2; WWC1; MNT; PGR; NFE2L2; RUVBL2; KLF6; PURA; ATF5; HMBOX1; HIPK3; KLF11; CBX6; ELF3; ZNF239; DLX5; NFE2L3; SKI; ZNF131; HOXB7; LOXL2; EMX2; DAXX; BCL3; YBX3; WT1; IRF8; FOS; ATF3; JUP; MEIS1; TBX3; NR3C1; HES1; RELB; ZNF586