Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID28205	Mitoxantrone	GSE70138	ASC	Human	24h	10uM	EID0104

Response Information :

Types	Number	Response transcription factors
Up-regulation	116	RELB; POU2F2; ACTL6A; HOXC5; HOXC4; ZNF532; SRCAP; CNBP; DLX2; SPIB; NFKBIB; GATA2; HMGXB3; IRF6; SREBF2; USP16; ERCC2; HMGB1; NOC2L; HAND2; ATF6; FOXJ1; PHOX2B; ESRRG; NHLH1; TAF4B; SLC2A4RG; GRHL2; TFDP1; FOSB; YEATS4; MYCL; TCF7; RING1; NFIX; MXD4; NEUROD6; TULP1; HIPK2; SUMO1; NR0B2; TBX10; SOHLH2; ZNF467; ACTL6B; NEDD8; TTF2; CEBPE; KLF7; SNAI1; HAND1; SPI1; DLX5; ZNF219; CSDE1; NR4A1; RBBP8; ELK4; CREBL2; GCFC2; ZSCAN18; EHF; TCF4; PAX6; ST18; VGLL1; MAK; TFDP2; AES; E2F1; GLI2; CHD2; HOXB1; ZNF117; ZNF224; MYT1L; ID1; NHLH2; INSM1; MYT1; ERBB4; PSIP1; BCL11A; CDK2; SSX1; E2F5; MYCBP; KLF13; NFE2L3; ZNF492; THRA; IRF9; TGFB1; MYBL2; GTF3A; ZNF551; NR2F1; CBX7; PAWR; NR5A2; ZNF711; DACH1; ZNF423; CD3D; DAXX; BACH2; MSX1; NKX2-1; NFATC3; TAL1; WNT4; ZNF91; ELK3; TP63; CREG1; NEUROD1
Down-regulation	144	NFIL3; CEBPD; CDK7; FHL2; XBP1; MYC; FOXO3; NFKBIA; TLE1; NUP62; ID2; CEBPB; SMAD1; REST; TBP; PATZ1; ADNP; RNF111; CEBPA; FOSL2; FOSL1; CTCF; PHF20; RLF; TBPL1; BTG1; ZNF217; MLX; PUF60; FOXJ3; USP22; RARA; TRIM32; HOXA5; SUV39H1; ZNF7; MED17; ZNF189; EGR2; CTR9; AATF; ARID5B; BRD8; ARNTL; SMARCE1; BHLHE40; PPARG; RBM14; SPEN; SOX4; ZMIZ1; ZFP64; ZNF131; NCOR1; EED; CHD1; NCOA6; PIR; SERTAD2; DDIT3; BHLHE41; NRBF2; RBBP4; ZNF292; IKBKAP; ZBTB24; DNAJC2; UBE2I; SNIP1; SAP30; DDX17; MED1; SCAND1; BRPF1; ZEB2; ZBTB38; CREB3L1; TAF4; PCGF1; ZNF12; TAF9; RNF4; CITED2; ZBTB11; TRIM28; POLR2A; NCOA4; DPF2; IRF2; RREB1; KAT7; RUNX1; FOXO1; VEZF1; AFF1; SFPQ; MITF; PNRC1; RRN3; ZFP36L1; NKX3-1; BRD3; WWTR1; NRIP1; TOB1; MNT; AHR; MYB; PCGF2; RYBP; BCOR; TRIM16; ZBTB1; SALL1; TFAP2C; TSC22D1; MGA; PHIP; KLF10; NFE2L2; TLE4; JARID2; NPAS2; SOX10; FLNA; KDM5A; TAF1D; KLF2; IRX5; CEBPZ; KDM5D; TRIP6; TEAD1; PITX2; RORA; PEG3; ZBTB16; IFI16; EGR3; TBX3; TOX3; TWIST1; HOXC6; BASP1