Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID27733 Rucaparib GSE70138 SKL Human 24h 0.37uM EID0098
Types Number Response transcription factors
Up-regulation 19 HMBOX1; WWC1; IRF4; PTTG1; HEY2; LMCD1; SOX10; LEF1; HTATIP2; NR2F2; CREM; FLNA; FOXL2; CREB1; HMGB3; HOXC6; EGR3; WT1; PEG3
Down-regulation 24 TULP3; FOXM1; ZBED4; YEATS4; STAT1; HMGA1; FOXE1; VDR; EYA1; NPAS2; VGLL4; TP63; ARID1A; FOXG1; TOB1; IRF6; BRD4; TOX; BRD2; KLF5; BCL11B; ZFP36L1; TFAP2A; ARNT2