Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID27643	Jq1-(+)	GSE70138	SKL	Human	24h	10uM	EID0098

Response Information :

Types	Number	Response transcription factors
Up-regulation	122	ATF3; CDK9; GATA3; IRF6; TAF4B; ZXDC; SMAD6; KDM5A; MNAT1; SOX12; SAP130; ZNF835; PRDM12; DAXX; CHD4; WNT4; RBBP5; CCNH; OVOL1; ZNF74; TBX3; VGLL1; IRX4; NR4A1; SAFB2; GCFC2; TP73; CDK2; BCL11A; REL; BRCA2; HOXD3; SIX3; THRA; GLI3; BNC1; SKIL; DBP; HOXD1; TRPS1; BRIP1; AGO2; WWC1; MECOM; NR5A2; PRPF6; GMNN; ZNF467; CBX4; HLF; DNMT1; SATB1; ITGB3BP; SPIB; SPI1; FOXG1; TBX1; MXI1; GRHL2; ID1; KLF11; NR3C2; MYBL2; ZNF12; HHEX; TFDP2; NR1H4; PCGF3; CDX1; SOX18; YAP1; MED15; GTF2F1; HDAC4; PHF20; BTG1; TFAP2A; TAL1; ID2; JUNB; KLF13; MAFF; ZMIZ1; ENO1; TTF2; HDAC1; TP63; HBP1; FOXM1; ARNT2; CBFA2T3; TWIST1; NR4A2; INSR; TEAD4; LITAF; KDM5D; ZBTB16; TFAP2C; CTBP2; NFE2L3; FOXF1; ZFPM2; PAX6; JARID2; CERS6; NR2F1; NFAT5; ERBB4; MYB; OSR2; TOX; CALR; EGR3; ID3; ZNF331; BCL11B; HMGA1; MYBL1; HMG20B; MEIS2; EMX2
Down-regulation	91	XBP1; FHL2; MEF2C; ATF1; PCBD1; MYCBP; TFEB; NCOR2; NUP62; BMI1; HOXA10; PPARG; MAGED1; TP53; IRF5; ARL2BP; ERBB2; TSC22D3; ZEB2; CRY1; TSC22D2; HMGA2; YAF2; TCF4; ZFP64; STAT6; WWTR1; ZNF432; ASCL1; ZNF532; HOXB7; ZNF329; TRIM22; TCERG1; ZBTB1; IRF8; SIAH2; POU2AF1; BAZ2B; HNRNPD; TCF12; NFYC; RNF10; HCFC2; SMARCD1; BAZ1A; SP3; RCOR3; VPS72; ELF1; LMCD1; SLC2A4RG; PKNOX2; ATF7IP; TFCP2; CBX5; TRAK1; ESR1; ARID4A; EYA1; TFEC; NCOA1; ZNF468; VEZF1; NFKB1; ATF4; BHLHE41; PCGF2; TLE4; MEF2A; HTATIP2; CHD9; PDLIM1; ZNF83; ZBTB38; EGR2; SOX10; SUB1; HOXC6; CREB3L2; NCOA2; HOXB2; TGFB1I1; HOXC10; SOX11; MSX1; PSIP1; LEF1; TXNIP; RELB; SUV39H1