Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID27212	Mk-1775	GSE70138	NPC	Human	24h	1.11uM	EID0090

Response Information :

Types	Number	Response transcription factors
Up-regulation	148	ARNT2; TRIB3; VDR; GMNN; CRYM; TBX1; TFAP2A; EN1; NR3C1; IRF6; SPDEF; ZNF350; PRDM12; MYBL1; ZNF557; PSMC3; PAWR; MAK; ZNF580; SRCAP; ELF4; TP73; RORC; SPI1; IRF9; HBP1; SKIL; PIAS4; NFE2L2; NFATC4; TRIM22; HIPK2; ZNF195; CDX2; ZNF267; HOXD1; NR1H3; NKRF; THRB; PCGF1; ZNF239; HOXA10; ZNF215; SOX18; LZTR1; MED14; CALR; SOX13; GRHL2; MNDA; HIC2; ERBB4; WNT4; ZNF394; TRIP11; ZNF112; BCL11A; MAFF; GFI1B; BNC1; NR5A2; TCF7L2; ATOH1; CERS4; HOXA3; CBX4; TEAD4; FOXE1; TP63; TFCP2; ZNF467; TFEC; MYCL; SP140L; REL; NFE2L3; ATF5; JUN; IRF8; ANKRD1; IFI16; TFCP2L1; NR1H4; CEBPD; CEBPG; ZNF175; SIX2; ZFP36L1; MAFB; ZNF91; ELF5; TGFB1; LOXL2; KAT2B; WT1; ST18; HHEX; TDP2; SNAI2; ZNF544; ZNF83; HOXA11; ZNF423; CNOT3; ZFHX3; TBX3; ZNF331; PAX5; ZNF665; WWC1; SPIB; EHF; ZNF165; EPAS1; NFE2; KLF13; MXI1; HLX; TOX3; PEG3; NANOG; MAF; TFAP2C; IRF7; FOSL2; BHLHE41; ZNF117; HOXC10; JUP; CREB3L2; POU2AF1; SATB2; JUNB; SOX17; HOXB6; RORA; NFATC3; HOXB2; CEBPB; TWIST1; LITAF; DLX5; TRPS1; MEIS2; YBX3; PBX3; BASP1; NR1H2
Down-regulation	119	NUP62; HNRNPD; THAP11; ATF1; BRCA1; EED; EZH2; HMGA2; HDAC2; DPF2; SOX4; TBP; DDX5; SMARCE1; SMARCC1; RBBP4; ZNF189; CBX3; PATZ1; TLE1; RHOA; BRD8; WHSC1; BRD3; HDAC1; VEZF1; MED4; CRY1; KMT2A; PBRM1; HDAC6; TFDP1; SIAH2; HLTF; ETV1; NELFB; IRX5; CREB1; CHD3; BMI1; MYCBP; PHF8; YBX1; NONO; MAGED1; MTF2; ING3; ERBB2; PIAS2; EDF1; CTCF; RBM14; UBE2I; DEK; HSF2; BRPF1; UBP1; RBPMS; RNF4; TRRAP; KDM2A; HMGN3; CBFB; ING2; YWHAB; BTF3; LPIN2; NFATC1; RBL2; PCGF2; NCOA4; ELK3; GTF2IRD1; ZMYM2; DNMT3B; CARHSP1; MSX1; HMGB1; ZMYND11; ZSCAN18; FOXO1; KAT6B; SFPQ; PAX6; TBL1X; ENO1; SMAD2; SOX11; BCLAF1; BATF3; IRF4; ZIC1; PURA; BBX; NR2F1; ELF1; TGIF1; RBBP7; GTF3A; TCEB2; ZNF652; MED1; ETS2; ZEB2; HMGB2; NKX2-2; BCL11B; ZFP36L2; KLF9; PBX1; CITED1; NR2F2; MYB; KDM5D; SUV39H1; ID4; PSIP1; LEF1; SMAD3