Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID26801	Belinostat	GSE70138	NPC.CAS9	Human	24h	10uM	EID0093

Response Information :

Types	Number	Response transcription factors
Up-regulation	123	FOXO4; STAT1; DRAP1; EGR1; PPARD; MYCBP; UBE2B; CREG1; WWC1; GTF2A2; CTR9; SETD3; FOXC1; CALCOCO1; PSMD9; HMG20B; PDLIM1; NOC2L; JUN; SMARCD3; RUVBL2; CRK; NR4A1; TSG101; MLX; FOSB; SIX1; ZSCAN32; MTF1; CCNH; MEF2D; CDK7; CRYM; CBX7; ZNF593; SNIP1; SIRT7; HDAC5; HBP1; FOS; TCF15; HDAC1; RXRB; ZNF205; HHEX; SIRT2; IRF7; SND1; CERS4; TAF10; DLX4; KLF2; ETV5; IL16; CEBPE; SIM2; RCOR1; ARID5B; CREB3L2; POU4F1; SERTAD2; NR4A2; DDIT3; SAFB2; USP16; PCGF1; SOX10; CBX4; TCF7; MAX; CCNC; GATAD2A; ZNF331; IRF9; MNAT1; HTATIP2; MXI1; RNF141; TAF12; RUNX3; ZNF224; JARID2; PIAS1; ATF3; TSC22D4; TGFB1; PPP1R13L; BCL10; TBX3; TOB1; CREM; TBPL1; PBXIP1; JUNB; MBD2; WWTR1; MLXIP; ARNTL; TERF2; PHF1; OSR2; CREB3L1; RUNX1; CEBPB; SP100; CITED2; NPAS2; BCL3; INSR; SOX9; HIVEP2; ELF5; PAX5; RYBP; BTG1; SUB1; ZBTB20; KLF6; EGR3; NFATC3; IRF8; TFAP2C; IRF6
Down-regulation	220	HMGA2; TP53; PCBD1; ATF1; SMARCA4; SOX2; NUP62; RFX7; MYBL2; HDAC2; USP22; FOXM1; EZH2; CCNA2; DDX17; LHX2; SOX11; LIN28A; HDGF; BAZ2B; ZBED1; VGLL4; RAN; TRIM24; GABPB1; XBP1; ZFP64; ZNF84; PHF2; ADNP; ZNF140; ZNF282; ZFP69B; TCERG1; SALL1; ZEB1; ZNF532; NFKBIA; BCOR; WHSC1; SUV39H1; MEIS1; BAZ1A; ZKSCAN8; STAT5B; ZFY; SSRP1; SLC2A4RG; TLE4; ZNF112; HNRNPD; MYCN; SCMH1; ZNF223; PLAG1; HOXB6; ZNF177; ZNF22; ZNF227; DDX5; ZNF32; ZSCAN16; EYA1; GTF3A; CENPF; PATZ1; CTCF; REPIN1; TAF9B; ZMYND11; ZNF529; PMF1; WDR77; ZNF614; CBX5; ELF4; BTF3; PHOX2B; ZBED4; ZSCAN31; NCOA2; YBX1; ZFP36L2; ABL1; PLAGL2; MDM4; VPS72; TBL1X; BRIP1; ZNF606; ZNF43; SALL2; ZIC3; CNBP; ZNF85; HMGB1; ERBB2; NONO; PMS1; DEK; CHD4; ZNF146; C1QBP; PROX1; ZNF141; ZNF292; NRIP1; ETV1; ZNF675; GTF2IRD1; SOHLH2; ZNF253; TGIF2; GTF2I; PRMT2; GLI2; ZNF93; ZBTB38; MEIS2; ZNF202; CREBL2; ZNF134; MYT1L; CHD3; PBRM1; PHIP; NFKB1; NCOR1; BCL11A; PAX6; ENO1; APEX1; ZNF232; TSC22D3; HIVEP1; HOXB2; ZNF512B; PBX1; ARL2BP; HMGB3; BPTF; HEY1; RBBP4; TOX3; FOXA2; BRD7; INSM1; PBX3; HIPK3; TAF1A; FOXG1; SOX17; HOXB5; ZMIZ1; KLF4; NCOA6; KLF3; ZKSCAN7; KAT2B; NEUROD1; ZNF33B; SP3; NFE2L1; PCGF2; DACH1; SMARCE1; CTBP1; FLI1; ZBTB1; NANOG; HMGB2; ZNF189; ZNF217; ISL1; SMAD1; ZNF467; TGFB1I1; ZNF573; RCOR3; LOXL2; CARHSP1; OLIG2; ZNF124; HAND1; BCLAF1; ZEB2; PSMC3; CTNNB1; HOXB7; NHLH2; MYB; CBFB; ZSCAN18; TCF12; ZMYND8; ZNF83; CUX2; NR2F6; HMGN3; DLX5; MTA1; HLF; MECOM; PLAGL1; ST18; ID4; TXNIP; TCF4; FOXO1; FOXN3; AEBP1; ID3; SMAD3; ID1; EMX2; ZFP36L1; IFI16; LEF1; ZFPM2; PSIP1