Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID26773	Sb-939	GSE70138	NPC.CAS9	Human	24h	10uM	EID0093

Response Information :

Types	Number	Response transcription factors
Up-regulation	130	FOXO4; GTF2A2; STAT1; PPARD; DRAP1; CTR9; SATB2; EGR1; CREG1; FOSB; FOXC1; CRK; HDAC5; CBX7; MYCBP; PSMD9; HMG20B; TSG101; UBE2B; MAX; JUN; HDAC1; TCEB2; KLF2; SETD3; ZSCAN32; WWC1; ZNF205; GTF2F1; CDK7; SMARCD3; MLXIP; PURA; YWHAB; TCF7; MLX; CEBPB; RXRB; ZNF331; HABP4; PCGF1; RUNX3; NR4A1; NOC2L; DLX4; JUNB; HTATIP2; BARX2; ECD; PHF1; SERTAD2; TAF10; ATF3; FOS; SOX10; CBX4; PBXIP1; NR3C2; IRX5; TOB1; NR4A2; SIRT7; CALCOCO1; SOX9; ELF5; BCL10; ZNF394; NFIL3; ZNF593; TCF15; SAFB2; CBX6; SIX1; ARNTL; CREB3L1; HLTF; DBP; DDIT3; MXI1; LYL1; ZNF430; RBBP5; IL16; RUVBL2; NEDD8; KLF6; VDR; CRYM; POU4F1; EGR3; SSX1; ZNF224; TBPL1; NFATC1; SSBP2; CREM; CALR; SPIB; MBD2; HBP1; WWTR1; CITED2; MED21; GATA2; HHEX; CREB3L2; IRF7; CD3D; SMARCA1; PITX1; INSR; HOXC10; ZBTB20; HIVEP2; NFIB; TLE2; KLF10; POU2AF1; BHLHE41; ASH2L; MED1; SMARCA2; TGFB1; PAX5; TP63; BCL3; TFAP2C; ZNF91; ID1; PSIP1
Down-regulation	232	HMGA2; PCBD1; TP53; SMARCA4; SMARCC1; SOX2; FOXM1; NUP62; ATF1; HDAC2; RFX7; XBP1; EZH2; ZBED1; CTCF; ZNF84; USP22; ZNF282; CCNA2; TFDP1; ZNF423; ZNF532; ZMYND11; ZNF227; ZNF134; LIN28A; NCOR1; ZNF112; CUX2; MEIS1; WHSC1; PLAGL2; HDGF; MYB; HOXB6; SETDB1; PHF2; WDR77; GABPB1; ETV1; PMF1; ABL1; ZIC3; VPS72; BCOR; HNRNPD; CTBP1; TCERG1; ZKSCAN8; SCMH1; SOX11; TGIF2; ZFP69B; VGLL4; ZBED4; SALL1; ZBTB14; ZNF232; EED; HIVEP1; ZNF140; ZNF22; MLLT10; DEK; ZNF180; PRDM1; ZNF141; PATZ1; HOXB2; ZSCAN16; ZNF146; WIZ; STAT5B; ARL2BP; ZFY; BAZ2B; WDHD1; TCF4; ADNP; ZNF45; BRCA1; NFKBIA; SALL2; SFMBT1; BRIP1; NCOA2; ASXL1; HIPK3; MYCN; SUV39H1; GLI2; ZFP2; NFYB; ZNF606; SOX17; ZSCAN31; ZNF43; FOXO1; ZNF253; CENPF; NFE2L1; IFI16; GTF2I; CBFB; ERBB2; TRIM22; HOXB5; RAN; ID4; ZNF202; TWIST1; TAF9; CBX5; HMGB2; GTF2IRD1; ZFP36L2; PMS1; RBL2; ZNF32; TAF9B; ZSCAN9; YEATS4; MDM4; SSRP1; TLE4; PBX1; ZNF189; SP3; ZNF292; PCGF3; POU5F1B; HMGB3; HOXB9; TGIF1; ZFHX3; ZBTB1; ZNF467; THAP10; ZNF85; NCOA6; HMGB1; NEUROD1; RNF138; ARID5B; BNC2; EMX2; ZNF329; TAF1A; TBL1X; GRHL2; MGA; CREBZF; TLE1; UBE2L3; TCF12; ZBTB38; ZNF33B; BRWD1; PHOX2B; FUBP1; CARHSP1; KLF11; NRIP1; ATN1; HMGN3; ZNF544; AR; APEX1; YAP1; NANOG; SOX5; EYA1; ZNF711; ZNF93; CHD3; SMAD3; ZFP36L1; GTF3A; ZNF124; KAT2B; MECOM; ZNF165; TAF1D; MYRF; NAB1; FOXN3; SIAH2; ELF4; MTA1; NHLH2; PBX3; SOHLH2; NFKB1; TOX3; ZMIZ1; MEIS2; PAX6; TFEC; ZHX2; SAP30; ZEB1; TCF7L1; BCL11A; ST18; AEBP1; PLAGL1; ISL1; SMAD6; SMAD1; ESR1; PCGF2; LOXL2; CREB1; DACH1; HIRA; TXNIP; RBBP8; GATA6; WT1; NR2F6; YBX3; ARNT2; INSM1; TGFB1I1; TFAP2A; BASP1; PEG3; ZIC1; ZFPM2; ZNF586; NFATC3; E2F2