Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID26655	Mk-1775	GSE70138	NPC.CAS9	Human	24h	3.33uM	EID0093

Response Information :

Types	Number	Response transcription factors
Up-regulation	126	TCEA2; CEBPD; CAMTA2; WWC1; ZNF580; CBX4; CRYM; EMX1; JUN; HOXB5; ZNF215; ZNF444; NR5A2; PRDM12; NFATC4; PAX1; ZNF331; HDAC9; RORC; PDLIM1; HOXB1; PCGF1; HOXB6; TP73; BHLHE41; IRF6; CERS4; VGLL1; PAWR; SOX18; ZNF816; TAF4B; LHX3; IRF9; HOXB2; HIPK2; WT1; CALCOCO1; ZBED2; ZNF688; SRCAP; JUP; BARX1; CEBPG; MYRF; KLF13; PRDM2; ATF3; TFEC; TP63; ZNF33B; HOXD1; FEZF2; CHD2; FOSB; CBX7; ZNF654; ZNF665; TFCP2L1; ST18; SOX17; ERBB4; IL16; ARNT2; CDIP1; PSMC3; DAXX; BNC1; ZNF423; BTG1; TRIM22; BCL10; TCF21; VDR; ZNF124; SP100; ZNF589; CREB3; EHF; HIC2; WNT4; LOXL2; NR4A2; ZNF551; ZNF264; CNOT3; OVOL2; HHEX; NFE2L3; ELF4; KLF10; HLX; NEUROD1; TRIB3; TGFB1; NR1H4; ID1; CITED2; IRF7; GATA6; KLF5; HOXB7; REL; NR4A1; TFAP2A; MAFF; NPAS2; ZFPM2; ELF5; FOXF2; ATF4; KLF4; OSR2; IRF8; POU2AF1; MEIS2; ZNF91; EPAS1; BCL3; MNDA; TOB1; NFATC3; JUNB; SNAI2; EMX2; PBX3
Down-regulation	104	EZH2; ATF1; NUP62; SOX4; CBFB; BRCA1; NACA; RBBP4; PURA; NONO; HDAC2; XBP1; RHOA; PHF8; YBX1; DDX5; RBBP7; TBL1X; HMGB1; TCERG1; BRD3; HNRNPD; BTF3; ORC2; SUV39H1; BMI1; SOX2; MED4; MED20; DDX17; CBX5; ZNF22; CNBP; MAGED1; LPIN2; DNAJC1; SOX11; NPM1; TRRAP; HSBP1; ENO1; DEK; SSBP2; CBX3; BAZ2B; WHSC1; ITGB3BP; PMS1; CHD7; ELK1; PHF2; YWHAB; BCLAF1; PIAS3; IRX5; CTBP1; GTF3A; VEZF1; BRD8; HMGB3; BAZ1A; ZFP36L2; SMARCA1; REPIN1; CHD3; PIAS2; SMARCE1; TRIM24; TGIF1; JARID2; ELF2; BLM; NR2F2; ZMYM2; PATZ1; PTTG1; ZNF516; FOXJ3; NKX2-2; RBPJ; DNMT3B; ZNF443; BCL6; RERE; CTNNB1; ZMIZ1; HLTF; FOXO1; TCFL5; RBBP8; MSX1; HMGB2; AFF1; SPEN; MYB; SIAH2; ASCL1; BCL11B; NFIB; NR1D2; LEF1; PSIP1; SMARCA2; KDM5D