Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID26617	Belinostat	GSE70138	NPC.CAS9	Human	24h	10uM	EID0092

Response Information :

Types	Number	Response transcription factors
Up-regulation	149	EGR1; DRAP1; FOXO4; STAT1; CDK7; NOC2L; CTR9; NR4A1; MYCBP; GTF2A2; PPARD; TAF4B; SOX10; FOSB; RUVBL2; CREG1; ZSCAN32; ZNF331; HDAC5; NR1H4; DLX4; PHF1; TOB1; DDIT3; TCF7; SIRT7; HCFC2; NR5A2; RING1; EZH1; ZNF324; ING2; EN1; CBX7; HMG20B; TBX19; TSG101; ZNF224; HHEX; C1D; TERF1; SSBP2; PAX5; SND1; NR4A2; FOXC1; IRX5; CBX4; TCEB2; CALCOCO1; ATF3; SPIB; USP16; JUNB; MLX; ZBTB48; MEF2A; CBFA2T3; PAWR; SNAPC4; KLF2; UBE2B; YBX2; SETD3; PCGF1; IL16; LHX6; SUPT4H1; ZNF394; PPP1R13L; ZNF593; IRF3; PFDN5; OSR2; LDB1; ZNF721; WWC1; EGR2; TAF12; HLTF; CITED2; ARNTL; SP110; LYL1; ZNF354A; SMARCD3; SERTAD2; MBD2; PURA; MYBL1; HDAC1; TFAP2C; BAZ2A; SIX1; INSR; POU4F2; CREB3L2; CREM; CSDC2; JUN; HOXD1; KLF6; TFEB; ZNF165; TBPL1; SSX1; MLXIP; NR3C2; NR4A3; NANOG; SMARCA1; HSBP1; CITED1; KDM4C; RUNX3; ETS1; CRYM; HBP1; IRF7; ZNF536; TGFB1; DBP; TLE2; BHLHE41; CREB3L1; PITX1; DNMT3B; ZNF160; LMCD1; POU2AF1; JARID2; ZBTB20; NR0B1; EGR3; TSC22D1; FOS; POU4F1; KLF4; SATB2; AHR; EPAS1; IRF8; TBX3; ARNT2; TFAP2A; CEBPB; MEF2C; PEG3; PSIP1
Down-regulation	170	NRIP1; TP53; HMGA2; PCBD1; SOX2; NUP62; XBP1; EZH2; HDAC2; ZNF282; FOXM1; SMARCA4; HDGF; TCERG1; ADNP; NCOR1; PHF2; GABPB1; ATF1; ZMIZ1; PATZ1; PMF1; NFKBIA; TCF12; USP22; PBRM1; HMGB3; SUV39H1; TSC22D3; SMAD3; WHSC1; RFX7; TBL1X; PARP1; PLAGL2; GLI2; SCMH1; ZNF532; ERBB2; ZMYND11; SP3; STAT5B; KAT2B; ZBTB1; ZFP64; CENPF; EED; HOXB9; CCNA2; ZNF84; DEK; REPIN1; PCGF3; IFI16; MEIS2; VGLL4; PRDM1; VPS72; ZNF22; ZBTB38; ZNF43; ZMYND8; SALL1; WDR77; LPIN2; MED17; NCOA2; MYBL2; ARL2BP; HOXB6; MYCN; SMAD6; ZNF292; TRIM22; TGIF2; ZBED1; BAZ1A; ETV1; NCOA6; PSMC3; MLLT10; ZNF146; VEZF1; ZNF248; ZFP30; SSRP1; BATF3; GFI1; SOX11; RBBP4; BRIP1; TAF9B; TRIM24; CHD3; CTBP1; ID4; ZNF32; ZEB1; ENO1; ZNF140; DACH1; SIAH2; ZNF189; DMTF1; MECOM; HNRNPD; FOXO1; RBL2; BATF; HIF1A; SIX2; CTNNB1; HMGB1; SCAND1; GTF2IRD1; PCGF2; CERS6; BCLAF1; SLC2A4RG; MAGED1; NR2F6; TOX3; TGFB1I1; FHL2; RBL1; KDM5D; CUX2; DLX5; TLE4; SOX17; BRD3; MEIS1; TCF4; MTA1; ZEB2; FOSL2; LOXL2; PIR; CARM1; YAP1; EYA1; CHD7; MED6; BMI1; ARNTL2; BCL11A; ABL1; TFEC; MKL2; GTF3A; TGIF1; E2F3; MEOX1; HIPK3; HOXB2; EYA2; TAL1; RXRA; MYB; SMAD1; TRIM16; HMGB2; PBX3; FOXG1; LEF1; ASCL1; MAFB; FLNA; ID3; NFATC3