Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID26590	Sb-939	GSE70138	NPC.CAS9	Human	24h	1.11uM	EID0092

Response Information :

Types	Number	Response transcription factors
Up-regulation	73	SMAD3; FOXO4; DRAP1; GTF2A2; CREG1; CTR9; ING2; PHF1; HMG20B; MAX; EGR1; BRD2; ETS1; STAT1; GTF2F1; SND1; JUN; MYCBP; CCNH; ALX1; RBFOX2; ARNTL; HDAC7; KLF2; TOB1; HDAC1; SOX10; CCNC; DNAJC1; JUNB; SIX1; TLE1; PBXIP1; PIAS1; SSX1; CITED2; BBX; BCL3; IRF7; CREM; CRYM; PHF20; MITF; NR2F1; PTTG1; ZFHX4; MYRF; KLF10; PFDN5; LMCD1; JARID2; FOXG1; MSX1; PITX1; FOXC1; TRPS1; MXI1; PBX1; SUB1; FOSB; NR4A1; NR2F2; MYBL1; OSR2; TGFB1; CEBPB; NR4A2; SNAI2; HEY1; ESR1; BASP1; ID1; PSIP1
Down-regulation	139	EZH2; TP53; PCBD1; HMGA2; ZNF282; ZBED1; ZMIZ1; SMARCC1; HDGF; TCERG1; BRCA1; FOXM1; CNBP; E2F1; ATF1; NUP62; CREBZF; NEUROD1; SMARCA4; XBP1; GLI2; MYCN; PATZ1; RFX7; ZFY; GABPB1; HIVEP1; BRIP1; ZNF219; SCMH1; PBX3; ZNF529; WHSC1; MYBL2; ZNF93; PHF2; TBX1; SFMBT1; NFKBIA; CUX2; ZNF180; NR1I2; CHAF1B; ZNF134; YBX1; CIZ1; DEAF1; SP3; BRCA2; ZNF84; HMGB3; IRX4; MLLT10; SREBF2; CBFB; YAP1; YEATS4; HOXA7; ORC2; BRWD1; ZMYND11; CERS6; DEK; DDX5; BCOR; ZNF43; ZNF468; AEBP1; DLX2; TAF1A; TAF9B; CTBP1; ZNF22; CAPN15; ZSCAN31; ZNF222; SLC2A4RG; PAX6; RBL2; SSRP1; ZNF189; GRHL2; SKI; SOX11; BATF; HIF1A; ZNF232; PLAGL2; REPIN1; BAZ2B; ZNF195; NKX2-1; ASCL1; FOSL2; PITX2; SALL1; ERBB2; ZNF107; ZNF165; LIN28A; AGO2; ZNF551; CHD7; TBL1XR1; ZNF124; MYB; HIPK3; TRIM24; ZBTB16; BCL11A; PHIP; E2F3; ZBTB38; FOXJ3; MYCL; TFDP2; MEIS1; NR2F6; GATA6; ZNF423; SIAH2; PLAGL1; ZSCAN18; TFEC; ZEB1; NKX2-2; ETS2; HLF; ZBED2; TRIM29; INSM1; PEG3; BAZ1A; KDM5D; MTA1; ZBTB18; NFATC3; E2F2; PPARG