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Overview Perturbagen Expression Profiles Transcriptional Responses
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Overview Perturbagen Expression Profiles Transcriptional Responses
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Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID26589 Sb-939 GSE70138 NPC.CAS9 Human 24h 3.33uM EID0092
Types Number Response transcription factors
Up-regulation 91 FOXO4; EGR1; STAT1; GTF2A2; CTR9; DRAP1; JUNB; PPARD; SERTAD2; MYCBP; CREG1; CCNH; ARNTL; HDAC1; HCFC2; HMG20B; SOX10; SETD3; TSG101; TBPL1; SSBP2; MLX; GTF2F1; SND1; JUN; UBE2B; COPS5; FOSB; TSC22D4; ING2; MBD2; SIX1; ZNF580; PIAS1; FOXC1; TAF10; ZNF44; ELF1; ELF5; CRK; PHF1; CALCOCO1; ZNF394; BCL3; AIP; RUNX1; NR3C2; NR4A1; TOB1; YWHAB; RUVBL2; TCF7; BBX; CREB3L1; ZNF721; BRD2; HLTF; MXI1; RBBP5; MAX; NKX3-1; ZNF160; USP16; NRBF2; ZNF593; CREM; ZFHX4; PTTG1; TFAP2C; ETS1; CEBPB; MITF; VDR; SP100; ERBB4; SOX9; JARID2; HMGA1; ETV5; KLF2; CRYM; MNDA; PITX1; INSR; IRF7; AHR; TSC22D1; EMX2; ATF3; RUNX3; FOS
Down-regulation 194 TP53; PCBD1; HMGA2; XBP1; NRIP1; ZNF22; SOX2; NUP62; ZNF84; ZNF282; SMARCC1; PATZ1; FOSL1; HOXB9; ZNF85; CTCF; ZNF93; PMF1; SALL1; CUX2; SMAD3; LIN28A; NEUROD1; ATF1; ZNF43; GTF2I; HOXB6; PARP1; RFX7; EZH2; DEK; ID4; ZNF711; EED; FOXM1; GLI2; SOX11; ZEB1; ZNF532; ZNF529; ZSCAN18; MED16; SMARCA4; ZNF253; HDGF; ZNF667; SLC2A4RG; SP3; NFKBIA; ZBED1; ZNF180; PHF2; VPS72; MYCN; TRIM27; TFDP1; ZNF134; PPRC1; ZNF33B; HIVEP1; ZKSCAN7; CNBP; MYBL2; HMGB3; TCF4; MED17; ADNP; ASCL1; PRDM1; HMGN3; TBX1; ZIC3; ZNF227; ERBB2; C1QBP; PBX3; ZNF135; ZFP64; SMAD4; EHMT2; BCOR; SIAH2; TGIF2; BRCA1; FOXF1; FLI1; ZNF140; HOXB5; RNF138; TGIF1; WHSC1; WDR77; MNT; TCF12; KLF7; HOXB2; PMS1; HIPK3; TRIM22; BAZ2B; TAF9B; ZNF273; GTF2IRD1; AEBP1; ZFP36L2; JAK2; ZBTB1; ZMYND11; KLF9; BRIP1; ZMIZ1; ZFPM2; ZNF195; ZSCAN16; PCGF3; MKL2; CTBP1; ZNF232; ZNF544; ZNF83; CARHSP1; HOXA7; KLF3; NCOA2; PSMC3; TOX3; MEOX2; ZNF551; CHD3; INSM1; NKX2-1; DNMT3B; MLLT10; NFYB; BAZ1A; MEIS2; SALL2; SOHLH2; FOXN3; ZNF189; CREB5; KLF1; TXNIP; ZSCAN31; KLF11; POU5F1B; HMGB1; PCGF2; DACH1; ZNF117; NKX2-2; PBX1; BCL11A; MEOX1; BCLAF1; TGFB1I1; ABL1; MYB; CEBPG; TBL1X; ZBTB38; GRHL2; NR2F6; NANOG; NR2F1; SCAND1; E2F3; REPIN1; TRIM24; MYCL; NFATC4; ARID5B; PSIP1; TDP2; PLAGL1; ZEB2; BACH2; YBX3; TLE4; HIRA; IRF6; HDAC9; TFEC; PAX6; EYA1; ZHX2; MEIS1; IRF8; ESR1; MTA1; ETS2; ID1; NFATC3; PPARG
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