Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID26588	Sb-939	GSE70138	NPC.CAS9	Human	24h	10uM	EID0092

Response Information :

Types	Number	Response transcription factors
Up-regulation	102	EGR1; DRAP1; FOXO4; STAT1; PPARD; CTR9; PSMD9; CDK7; MYCBP; CEBPA; FOSB; JUNB; CREG1; TSG101; GTF2A2; RUVBL1; MLX; HDAC5; SETD3; SERTAD2; RUVBL2; NR4A1; NOC2L; HMG20B; HDAC1; SMARCD3; SSBP2; SIX1; DLX4; SND1; TOB1; GTF2F1; BRD2; ZNF593; TAF10; ZNF331; ECD; IRF7; MNAT1; ZSCAN32; ARNTL; SNIP1; DDIT3; CRK; CCNH; PHF1; RXRB; ETS1; IRF3; MAX; MEF2D; PCGF1; FOXC1; TAF12; CBX7; CALR; ZNF394; NR4A2; FOS; KLF2; NR3C2; JUN; CALCOCO1; CCNC; ATF3; RUNX3; MLXIP; CRYM; TBPL1; TCF7; USP16; PPP1R13L; EGR3; CREM; HLTF; UBE2B; LYL1; TGFB1; CITED2; MSX1; SPIB; SATB2; CEBPB; INSR; NFIC; CREB3L2; KLF6; HMGA1; NR0B1; POU4F1; KLF10; CREB3L1; PITX1; BCL3; OSR2; JARID2; HHEX; POU2AF1; TFAP2C; MXI1; KLF5; PSIP1
Down-regulation	230	NRIP1; PCBD1; TP53; HMGA2; SOX2; TCERG1; NUP62; SMARCC1; USP22; XBP1; FOXM1; RFX7; ADNP; PATZ1; EZH2; ZNF282; ZNF84; HDAC2; MYCN; GABPB1; SMARCA4; PMF1; ATF1; ZNF532; SMAD3; LIN28A; GLI2; ZNF43; ZNF675; ZFY; SUV39H2; SALL1; HDGF; ZNF22; ZMYND11; SOX11; ZMIZ1; ZNF141; HMGB3; CREBZF; GTF2I; ZBTB6; PHF2; NCOA2; CUX2; ZNF711; MLLT10; HOXB9; ZNF529; ZBED1; HIVEP1; SCMH1; NCOR1; ERBB2; ZIC3; SETDB1; LZTS1; KAT2B; ZKSCAN8; CTCF; ZNF219; CBX5; TAF9B; ZFP64; YEATS4; ZNF292; ZNF227; ZNF112; TRIM22; BRIP1; PRDM1; ZFP2; ZNF33B; SP3; TBL1X; ETV1; BCOR; TOX3; CREB1; ZNF682; MEIS2; NFKBIA; ZBTB1; VPS72; ARL2BP; LHX2; ZNF287; UBE2L3; ZBTB38; WHSC1; HNRNPD; CARF; DEK; BCL11A; PCGF3; ZNF134; NEUROD1; ZNF253; SALL2; SMAD6; GTF2IRD1; ZSCAN31; APEX1; CTBP1; WDR77; VGLL4; MEIS1; ZNF74; SUV39H1; TGIF2; TFEC; HOXB6; ZFP69B; ZEB1; BRWD1; ZNF189; PLAGL1; RSF1; ZNF140; ID4; TCF12; PLAGL2; PCGF2; ZKSCAN7; PBX3; ABL1; BATF; SREBF2; TAF1D; ZNF93; TBX1; TLE4; ZNF423; KLF3; HIPK3; CHD3; RAN; C1QBP; BCLAF1; NFYB; ZNF467; PGR; ZNF107; ZNF248; WDHD1; SMARCC2; ZNF124; CCNA2; TCF4; HMGN3; RBL1; MYB; ZFP36L2; CARHSP1; BAZ2B; ASCL1; TGFB1I1; REPIN1; INSM1; STAT6; YAP1; FHL2; RBPJ; HIF1A; NANOG; TBL1XR1; SOX17; PMS1; ZNF232; ZNF551; TRIM24; E2F3; IFI16; PHOX2B; PBX1; ELF4; ZNF32; ARID5B; JAK2; ENO1; DDX17; SIAH2; GRHL2; HMGB2; TGIF1; RNF138; FOXN3; BAZ1A; PIR; NFKB1; MYCL; E2F5; AEBP1; KDM5D; EYA1; PAX6; MTA1; RBBP4; ZFPM2; NFATC4; MECOM; MKL2; ZNF217; NR2F6; ZNF83; SCAND1; HIRA; ZHX2; LOXL2; GATA6; SMAD1; MAGED1; NR2F1; BNC2; FOXF1; HMGB1; ZEB2; TAL1; HOXB2; NKX2-1; DACH1; LEF1; DAXX; HLF; FOXO1; EMX2; WT1; ZSCAN18; ETS2; NFATC3