Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID26536	Acy-1215	GSE70138	NPC.CAS9	Human	24h	10uM	EID0092

Response Information :

Types	Number	Response transcription factors
Up-regulation	88	SMAD3; FOXO4; DRAP1; STAT1; EGR1; CREG1; COPS5; RUVBL1; MYCBP; CTR9; SOX10; CCNH; RUVBL2; ARNTL; SERTAD2; HMG20B; HEY2; LMCD1; MTF1; JUN; NR1H4; PHF1; HMGA1; SUPT5H; TBPL1; IRF3; SND1; MYBL1; ENY2; DLX4; MLXIP; ETS1; IRF2; PTTG1; TAF10; CALCOCO1; ZNF580; LYL1; ZNF593; CEBPB; JUNB; FOSB; WWC1; MITF; ANKRD1; KLF2; IRX5; MBD2; ZNF721; NR3C2; IRF7; ELF1; TCF7; PIAS1; CREM; SIX1; CBX7; POU2AF1; INSR; HTATIP2; ZNF331; TOB1; NR4A1; TCF7L2; JARID2; NR4A2; HDAC1; SMARCD3; TSC22D1; CREB3L1; SPIB; SATB2; CRYM; STAT4; BCL3; SMARCA2; MXI1; EGR3; PAX5; AHR; RUNX3; FOXC1; TLE1; OSR2; ZBTB18; NR2F2; LEF1; BASP1
Down-regulation	141	TP53; PCBD1; HMGA2; FOSL1; ATF1; TCERG1; ZNF282; PMF1; ZNF84; NRIP1; YEATS4; EZH2; HDAC2; SUV39H1; GTF2I; ZBTB1; GABPB1; GLI2; ZNF134; SOX2; SLC2A4RG; ZNF177; VPS72; PATZ1; ZBED1; PPRC1; DEK; BRCA1; STAT5B; HOXB6; BCLAF1; TAF9B; BRIP1; TAF1D; CCNA2; SFMBT1; ZNF227; HOXB9; SETDB1; MYBL2; BCOR; RBBP4; HDGF; WHSC1; ZNF112; ZMYND11; MLLT10; PCGF2; ZNF274; CNBP; HIVEP1; ZBED4; MED17; NFKBIA; FOXO3; CARHSP1; RFX7; FOXM1; TOX3; NFYB; ZEB1; TRIM22; DPF2; HMGB3; DACH1; ADNP; ERBB2; CIZ1; GTF2IRD1; SMARCE1; RBL2; SOX11; ZSCAN31; ARL2BP; SP3; ZNF22; MYCN; DDX5; ZMIZ1; C1QBP; ZNF107; ZNF711; TGIF2; PITX2; BATF; EHMT2; HIPK3; CREB1; ZBTB38; TBL1XR1; PLAGL2; ZNF532; ZNF140; HOXA7; ZNF189; HOXB5; TCF4; PSMC3IP; BMI1; PAX6; FOXF1; TBL1X; MYB; NR2F1; MYCL; ZNF302; ZNF43; RNF138; MEIS1; ZNF432; TCF12; ZNF551; HNRNPD; SALL1; FOXA1; AR; FOXF2; ZNF32; ARID5B; ZNF232; CBFB; ZFP36L2; PBX3; DMTF1; TGIF1; SIAH2; HOXB2; NKX2-1; MEIS2; BAZ1A; AEBP1; ZSCAN18; ASCL1; ZIC1; NR2F6; ZBED2; MAFB; ZFPM2; ID4; ESR1; NFATC3