Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID26472	Mk-1775	GSE70138	NPC.CAS9	Human	24h	1.11uM	EID0092

Response Information :

Types	Number	Response transcription factors
Up-regulation	55	TSC22D3; CAMTA2; ATF4; DLX5; GLI2; PAWR; PCGF1; SNAI2; RARG; HTATIP2; ZNF131; JUNB; CEBPG; NFE2L2; BHLHE41; TRIB3; BBX; NCOR2; ZBTB38; ATF5; CREB3L1; VDR; USP16; NPAS2; NR1H4; GTF3A; EMX2; PIR; DDIT3; CRYM; MNAT1; MECOM; RUNX1; YBX3; ZSCAN31; LITAF; CEBPB; DLX2; NR1D2; TGFB1; NFATC3; TCF21; NFAT5; IRF8; TP63; SOX9; TOB1; FLNA; TFAP2A; MEIS1; ARNT2; KLF5; ZIC1; PEG3; PSIP1
Down-regulation	97	CRK; ZMIZ1; EZH2; CHD7; SOX2; NUP62; SMAD4; BRCA1; HMG20A; ATF1; SP3; SAP30; RBM14; NPAT; HMGB3; NAB1; RCOR3; SUV39H1; ELK3; NPM1; ZNF43; TAF7; MYBL2; ITGB3BP; ZNF107; ZNF93; TCF12; RLF; BRD3; BCL6; ZNF273; FOXJ3; JUND; ZNF443; CBX3; ZBTB18; IRF2; TCF7L1; SALL2; BLM; TRIM32; BCL10; CENPF; ZNF281; PBXIP1; ETV1; RBBP4; MAML1; JARID2; TRIM24; ZNF430; TCF3; TCF7L2; ZFP36L2; RARA; CRY1; PSMC3IP; NR2F1; ZNF189; TBL1XR1; SOX13; CNOT2; HMGB2; INSR; RREB1; ZNF217; CHD9; ISL1; ID4; DNMT3B; PBX1; ZKSCAN1; AFF1; LPIN2; FOXO1; MEIS2; ARID5B; ZBTB16; TXNIP; ZNF91; RAD21; TAL1; ASCL1; TOX; ZEB2; ZEB1; TRPS1; TGIF1; NR2F2; SMAD1; PBX3; IFI16; MXI1; TFAP2C; CITED2; ZFPM2; MYB