Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID26471	Mk-1775	GSE70138	NPC.CAS9	Human	24h	3.33uM	EID0092

Response Information :

Types	Number	Response transcription factors
Up-regulation	110	TCEA2; PSMD9; ING4; ZNF132; SSX1; ZNF225; STAT1; EMX1; CALCOCO1; PPP1R13L; E2F2; ZNF580; CBX4; OLIG2; JUN; PRDM12; EGR1; CDIP1; HIPK2; LZTR1; EN1; NEUROD1; MYRF; L3MBTL1; ZNF33B; VGLL1; PRDM2; MECOM; SIM1; BNC1; PHF1; HDAC5; CREM; ELF4; HOXB1; NFE2L2; ZNF557; CREB3; JUNB; BARX1; FOSL2; SOX13; PNRC1; TFEB; PAWR; SRY; ZNF264; ANKRD1; FOXF2; LYL1; CSDC2; TRIB3; HEY2; SKIL; NR0B1; NANOG; ZNF331; ABL1; MAFF; TULP3; MXI1; NKX2-2; ZNF423; PTRF; TLE2; LITAF; VDR; DDIT3; POU2AF1; BHLHE41; HOXC10; ZNF83; STAT4; TGFB1; KLF6; RORA; TFAP2A; IRF6; FOXG1; JUP; SMAD7; SNAI2; HBP1; NR1H2; TWIST1; CEBPB; ARNT2; BCL11A; ELK3; SATB2; PAX5; IRF9; LOXL2; GATA6; MEIS2; SOX17; MYBL1; TFEC; PLAGL1; HMGA1; HHEX; ID3; KLF2; ZBED2; PBX3; IFI16; HOXB2; KDM5D; ATF3; FOS
Down-regulation	69	SOX2; EZH2; KAT6A; NUP62; SUV39H1; BRCA1; TRRAP; WHSC1; RBBP8; NCOA1; SAP30; RBL2; CBX3; SSRP1; PURA; HMGB3; RBBP4; RHOA; FOXL2; GLI2; PIAS3; RBM14; TBL1X; SETD2; RNF138; SMARCE1; TRIM24; NPAT; ING2; PLAGL2; BCL11B; CHD1; PMS1; CREB1; NCOA6; BLM; HMBOX1; CRY1; ATF7IP; ENO1; HNRNPD; JARID2; PRKDC; TCF7; BCLAF1; ASCL1; RERE; MAF; DNMT3B; ZEB2; NR2F2; SMARCA2; PSIP1; AFF1; SCAND1; TOX3; ID2; RREB1; PBX1; ETS2; NFAT5; NR2F1; BAZ1A; MSX1; DACH1; MYB; ZIC1; ID4; NFATC3