Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID26433	Belinostat	GSE70138	NPC.CAS9	Human	24h	10uM	EID0091

Response Information :

Types	Number	Response transcription factors
Up-regulation	125	EGR1; FOS; FOXO4; DRAP1; STAT1; HMG20B; FOSB; GATA2; PPARD; NOC2L; CRK; CALCOCO1; JUN; DLX4; ZNF324; NR4A1; GTF2A2; APBB1; HDAC1; CTR9; CREG1; GTF2F1; TSG101; BRD2; HOXA10; MYCBP; SPIB; TAF4B; UBE2B; HABP4; KLF2; CDK7; ZNF224; HOXB1; TCF15; CEBPE; SND1; RUNX3; NR4A2; EN2; ZSCAN32; EVX1; CBX7; MYBL1; ZNF331; RUVBL2; ZNF160; TCF7; LHX6; SOX10; ATF3; BRF2; SIRT7; NRBF2; HBP1; MNAT1; OSR2; RBBP5; BRD4; JUNB; NR3C2; JARID2; ZNF593; DDIT3; IL16; TBPL1; CRYM; ZNF587; MBD2; HHEX; ZNF721; NR4A3; TAF10; ARNTL; ZNF611; COPS5; TOB1; KLF6; NR1H4; SERTAD2; YWHAB; WWP1; CERS4; TERF1; TCEB2; HLTF; POU4F1; SIX1; CREM; ZNF44; TLE2; IRF7; MITF; JUND; TGFB1; WWTR1; ETV5; MXI1; ETS1; FOXC1; ZBTB20; EGR2; SATB2; PAX5; SP100; ELF5; CCNC; EGR3; NR0B1; EPAS1; PTTG1; LYL1; TP63; HOXD1; MLXIP; ADRB2; IRF8; FOXD1; AHR; BTG1; ZNF91; BHLHE41; CITED2; SNAI2; PSIP1
Down-regulation	204	HMGA2; PCBD1; TP53; NUP62; ATF1; XBP1; SMARCA4; EZH2; NR2F6; CCNA2; ETV1; PHF2; ZBED1; SP3; ZNF282; HDAC2; BRIP1; HDGF; ADNP; RFX7; VPS72; TCERG1; MYBL2; PATZ1; GABPB1; GLI2; WHSC1; ZFP64; ZNF146; PLAGL2; STAT5B; FOXM1; ZNF140; ZNF467; PMF1; WDHD1; TCF12; MYCN; MLLT10; ZNF84; PCGF2; E2F3; ZMIZ1; ZNF22; HNRNPD; ZFP36L2; CARHSP1; DEK; NCOR1; VGLL4; ZNF189; NRIP1; BAZ1B; ZFP30; CBX5; GTF2IRD1; ZNF292; MYB; ENO1; SOX11; BCL11A; ZNF43; BRD3; ZMYND11; HMGB3; CTCF; ID4; PKNOX1; ELF2; BAZ2B; ZEB1; ZNF532; CTBP1; FOXO3; NAB1; UBE3A; SCMH1; RBM14; BRCA1; RBPJ; SSRP1; PBX3; STAT6; ERBB2; USP21; BAZ1A; BACH1; ZNF423; SREBF2; ZKSCAN7; MED17; SSBP3; ZBTB38; SETDB1; TCF4; BATF3; PMS1; ZNF32; ZBTB1; CHD3; ZNF711; ZNF629; ARNTL2; MEIS1; IFI16; TAF9B; YEATS4; MTA1; SALL1; REPIN1; MGA; CNOT1; ABL1; FOXN3; NFKBIA; ZNF302; PCGF3; NCOA6; LIN28A; TOPORS; SAP30; SALL2; MAGED1; TBL1X; ZNF232; ZNF24; BCLAF1; ELF4; TRRAP; CUX2; ZBED4; ZNF134; CHD9; UBE2L3; SOHLH2; DEAF1; TBL1XR1; YBX3; PAX6; NFYB; TADA3; MAFB; SMAD1; RBBP4; TGIF2; TRIM24; RNF138; SLC2A4RG; MKL2; KDM5D; RXRA; GTF2I; EED; HLX; NCOA2; ZNF85; ZNF107; EMX2; ZFPM2; ERF; SIX2; ISL1; TRIM29; ARID5B; NCOR2; HMGB2; CTNNB1; HOXB6; SMAD6; PBX1; SMAD3; ZNF124; GTF3A; NCOA1; HIPK3; ZNF512B; SCAND1; HMGN3; HIC2; MYC; RBBP8; ZHX2; TFEC; BNC2; MEIS2; TLE4; ZSCAN31; TGFB1I1; ZMYM2; ZNF217; SIAH2; CERS6; FOXO1; ASCL1; BCL6; BMI1; HOXB2; PEG3; MECOM; GATA6; SUV39H1; FLNA; NFATC3; GATA3