Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID26406	Sb-939	GSE70138	NPC.CAS9	Human	24h	1.11uM	EID0091

Response Information :

Types	Number	Response transcription factors
Up-regulation	70	FOXO4; CCNH; HES1; GTF2A2; PPARG; HMG20B; CREG1; JUN; DRAP1; SOX4; EGR1; SATB1; STAT1; MAX; SOX10; ZNF224; TBPL1; LMCD1; IRF7; CREM; CRYM; RUVBL2; HEY1; CTR9; ARNTL; RBBP5; ZNF160; BHLHE41; BCL3; RYBP; MBD2; MYCBP; TLE1; SERTAD2; ETV5; KLF2; TCF7L2; RUNX1; ZNF721; MXI1; CREB3L2; AHR; PTTG1; FOSB; SIX1; SIM2; CALR; ZBTB18; BBX; ELF5; IL16; TOB1; TCF7; CTBP2; YWHAB; SSBP2; SNAI2; SOX9; KLF10; CREB5; MSX1; HLTF; BTG1; NR4A2; FOXC1; NR3C2; MTF2; SATB2; MYRF; NFIB
Down-regulation	123	PCBD1; HMGA2; TP53; ATF1; NUP62; NR2F6; MYBL2; SMARCA4; BRCA1; TCERG1; EZH2; PHF2; ZNF282; BRIP1; WDHD1; SREBF2; HDGF; GLI2; SP3; TSC22D3; ZEB1; FOXM1; ZBED1; NFKBIA; ZNF84; RFX7; PLAGL2; RBL1; TTF2; HNRNPD; PATZ1; DEK; CTCF; ZFP36L2; TAF9B; ZNF629; CARHSP1; CUX2; DNMT3B; LIN28A; SLC2A4RG; SCMH1; E4F1; PBX3; PMF1; ARNTL2; ZBTB24; MYCN; NCOA2; CHD3; YEATS4; RBM14; MYB; ZBTB38; DEAF1; ZIC3; UBE3A; E2F8; ZNF532; CARM1; TRIM22; WHSC1; RNF138; CBX5; HOXB2; PHOX2B; ZSCAN31; CNBP; FOXE1; ZNF232; BCLAF1; ERBB2; MAGED1; ZNF43; HMGB2; SALL2; CBFB; GRHL2; RXRA; TRIM24; ERF; MEIS2; ISL1; ZHX2; SIAH2; ELF4; PSMC3; EYA1; CTBP1; ABL1; ZNF512B; AEBP1; ARID5B; KAT6B; NFE2; MYCL; MEIS1; TCF4; AR; HOXB6; FOXF1; SALL1; HIC2; TFEC; BCL11B; HIPK3; ZSCAN18; POU2AF1; TBL1X; MTA1; HLF; HDAC9; SMAD3; LEF1; PEG3; NRIP1; PSIP1; SUV39H1; ESR1; SMAD1; NFATC3; E2F2; GATA3