Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID26405	Sb-939	GSE70138	NPC.CAS9	Human	24h	3.33uM	EID0091

Response Information :

Types	Number	Response transcription factors
Up-regulation	83	EGR1; FOXO4; STAT1; PSMD9; HMG20B; GTF2A2; CREG1; HDAC1; JUN; DRAP1; FOS; KDM5A; DLX4; CTR9; CRYM; SIX1; SETD3; NR4A1; FOSB; JARID2; BRD2; MXI1; NR4A2; RBBP5; E2F2; GTF2F1; SOX10; TBPL1; BAZ2A; PURA; TCF15; KLF2; SPIB; TOB1; MYCBP; ZNF205; SIRT7; SSBP2; ELF5; MAX; IRF7; SERTAD2; CTBP2; PPARGC1A; YBX2; ETV5; WNT4; ZBTB43; EGR3; RCOR1; CREB3L2; MBD2; SP100; ATF3; CERS4; NR3C2; EDF1; SIM2; FOXJ1; NFIB; FOXC1; NFAT5; MYBL1; ETS1; NFATC3; EYA1; RUNX3; BBX; CREB3L1; MSX1; TGFB1; HOXC6; SOX9; ZNF331; EYA2; HOXC10; BTG1; JUNB; PITX1; MTF2; NR0B1; NR2F2; PSIP1
Down-regulation	164	PCBD1; HMGA2; TP53; CCNA2; NUP62; ATF1; MYBL2; NR2F6; SMARCA4; EZH2; GLI2; SMARCC1; VPS72; XBP1; ZFP36L2; ZNF189; PPRC1; ZNF282; TSC22D3; ZNF146; ZNF140; HDGF; PHF2; ZHX2; BRCA1; SOX2; FOSL1; E2F3; PATZ1; ZEB1; TOX; RFX7; SMAD4; TRIM27; SFMBT1; ZNF84; SCMH1; PLAGL2; BRIP1; HNRNPD; MKL2; CHAF1B; ZNF202; DEK; MLLT10; ZNF529; HIVEP1; TCF4; NCOA2; ZNF22; ZNF43; CEBPG; SOX11; ZKSCAN7; ZNF93; TCF3; ZNF134; CARHSP1; NFYB; ZMYND11; KLF7; ADNP; CREBZF; TAF9; RBM14; ZNF292; ZNF532; PMF1; ZNF219; ZNF423; ZBED1; ZNF45; ZFX; LIN28A; SOHLH2; ZBTB38; SSRP1; BRWD1; FOXM1; C1QBP; REPIN1; DPF2; ZFPM2; ZNF227; ZNF85; TFEC; MYB; APEX1; ARL2BP; SALL1; ZNF302; ELF4; ERBB2; ERF; ZNF232; MYCN; RBPJ; SF1; TAF9B; PAXBP1; TGIF1; BCL11A; ZNF711; PBX3; WHSC1; CTNNB1; BAZ2B; RBM39; SIAH2; YAP1; YAF2; TRIM24; TRAK1; TAF1D; FOXE1; NFKB1; ZNF195; TRIM22; ZNF107; PCGF2; ARID5B; MEOX2; HIPK3; NANOG; TGFB1I1; ABL1; HMGB3; LEF1; BAZ1A; ZNF32; BIRC2; PSMC3; FOXF1; ZNF131; ZNF281; HIC2; AEBP1; FOSL2; MEIS2; ZNF512B; SMAD3; PBX1; SOX17; POU2AF1; HLX; ZMYM2; FOXF2; HDAC9; HOXB6; MTA1; ZSCAN31; ZSCAN18; TLE4; EMX2; NRIP1; GATA6; HMGB2; FOXO1; ID4; PEG3; SUV39H1; TOX3; ARNT2; GATA3