Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID26404	Sb-939	GSE70138	NPC.CAS9	Human	24h	10uM	EID0091

Response Information :

Types	Number	Response transcription factors
Up-regulation	118	GATA2; EGR1; FOXO4; FOS; DRAP1; CTR9; STAT1; FOSB; HMG20B; TSG101; GTF2A2; PPARD; CCNH; CRK; SETD3; NR4A1; SND1; BRD2; JUNB; HDAC1; NR4A2; CREG1; ZNF331; JUN; ZNF324; DLX4; BCL10; NFIL3; MYCBP; HBP1; RUNX3; EGR3; HDAC5; RBBP5; PSMD9; KLF2; GTF2F1; NAB2; MLX; TAF10; EVX1; SAFB2; CREM; RUVBL2; CEBPE; TCF15; MEF2D; CDK7; DDIT3; MSX1; ZNF160; IRF7; RYBP; SNIP1; OSR2; TBPL1; ZNF224; PHF1; TGFB1; RXRB; NR0B2; HLTF; NR4A3; TSC22D2; C1D; IL16; COPS5; ETS1; ZNF587; SMARCD3; UBE2B; SPIB; CREB3L2; DBP; TCF7; ZNF721; HHEX; ARNTL; CEBPB; CBX7; ECD; MAFG; YWHAB; JUND; SATB2; BRD4; ZFHX4; JARID2; SIX1; BCL3; NFIC; CALR; MDM2; EGR2; ZNF593; PTRF; WWTR1; INSR; CCNC; ATF3; LYL1; SERTAD2; KLF6; ID1; EPAS1; TOB1; CITED2; NR3C2; IRX5; AHR; IKBKAP; HOXD1; SMARCA1; TRIP6; SOX9; TFAP2C; ESR1; PSIP1
Down-regulation	239	HMGA2; PCBD1; TP53; NUP62; CCNA2; NR2F6; RFX7; PARP1; EZH2; XBP1; SMARCA4; ETV1; GLI2; FOXM1; VPS72; VGLL4; USP22; ATF1; HDAC2; HDGF; ZNF22; BRIP1; MLLT10; ZBED1; CBX5; MED17; NCOR1; ZMIZ1; TAF9B; NRIP1; PATZ1; BACH1; WDR77; ZNF711; TBL1XR1; ZNF43; MYBL2; ZNF675; ZNF84; ZMYND11; WDHD1; ZNF423; ZNF282; TSC22D3; TTF2; ID4; BRCA2; PHF2; HNRNPD; ZBTB1; ADNP; SCMH1; CTBP1; HMGB3; NEUROD1; ZFP36L2; ZFP69B; RBBP4; SALL1; PMF1; CTCF; ZFP30; ZNF682; PRDM1; ZNF236; ZNF107; ZNF32; NCOA2; CUX2; SUV39H2; KAT2B; RAN; ELF2; ARL2BP; CHAF1B; ZBED4; CARHSP1; RBL1; USP21; YEATS4; ZNF529; PKNOX1; LIN28A; SOHLH2; ERBB2; MDM4; ZNF232; E2F3; ZFP64; BAZ2B; BCLAF1; TCF4; ZNF141; ZNF112; ABL1; SOX11; ARNTL2; BCOR; HMGN3; SETDB1; ZKSCAN7; NFKBIA; MYCN; ZNF33B; LZTS1; ZNF253; NFYB; UBE3A; HIVEP1; CREB1; BAZ1A; ZNF227; PCGF3; PITX2; ZNF292; WHSC1; SMARCB1; ZEB2; ZNF140; YBX3; ZFP2; ZNF493; STAT6; PLAGL2; JAK2; PBX3; PMS1; ZNF146; PCGF2; LHX2; TRAK1; FUBP1; ZNF45; ZNF85; MAFB; BRD3; DDX17; C1QBP; MKL2; MAGED1; ZEB1; ZNF302; CAPN15; PKNOX2; TCF12; HMGB1; UBE2I; SSRP1; ZNF248; ZNF532; INSM1; SLC2A4RG; ZNF117; SMARCC2; TLE4; ZNF273; BAZ1B; FOXN3; UBE2L3; MYCL; RBM39; PAX6; TFEC; ZNF134; EYA1; BRD7; ZIC3; E2F8; CREBZF; SALL2; ZNF551; NCOA1; GATA4; DEK; OLIG2; TGIF1; MEIS2; TRIM29; GATA6; BCL6; RNF138; PQBP1; MEIS1; LEF1; ZNF93; REPIN1; ZFPM2; POU2AF1; ZNF195; ARID5B; MYB; CREB5; MTA1; IFI16; ZSCAN31; IRF6; SMAD3; MECOM; FOXF2; TBL1X; GRHL2; TCF7L1; BCL11A; HOXB6; CBFB; SIX2; ZMYM2; GTF2I; NKX2-1; PHIP; ZHX2; SMAD1; MEOX2; LOXL2; PIR; TRIM22; AEBP1; NFE2L3; SIAH2; NCOR2; HMGB2; BNC2; PDLIM1; PLAGL1; ZBTB18; TXNIP; TOX3; TGFB1I1; ST18; ZNF589; ZIC1; HLF; FOXG1; HOXC6; ASCL1; SUV39H1; CEBPD; E2F2; NFATC3