Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID26346	Agk-2	GSE70138	NPC.CAS9	Human	24h	10uM	EID0091

Response Information :

Types	Number	Response transcription factors
Up-regulation	118	ZNF586; JUN; THRB; MAFF; SKIL; BHLHE41; ZNF264; ZNF544; ZNF350; ZNF208; ZNF155; ZNF749; ZNF304; CEBPG; ZNF665; FOS; MNDA; POU1F1; ZNF682; ZNF239; MYNN; ZNF551; POU2F3; ATN1; SIX6; SOX17; ZNF587; ATF4; ZNF91; ZNF394; FOSB; FEZF2; VDR; ZNF419; ZNF175; OVOL2; KLF3; CEBPB; GATAD2A; SOX18; ZNF415; TRIB3; ZNF222; LOXL2; ZNF44; TRIM22; FLI1; ACTL6B; DAXX; NPAS2; IRF9; PHF1; ZNF83; ZNF195; RXRG; DNAJC2; TFAP2A; TCEA1; ZNF580; ZNF93; IRF6; MECOM; ZNF43; DDIT3; TEAD4; SP100; TCF7; HDAC9; MYC; NKX3-1; NR1H4; TOX; ZNF593; ZNF331; ETS1; CREB5; ZNF430; TRIP6; ZIC1; BCL6; KLF4; NANOG; EMX2; SOX9; CBX7; SPDEF; HMGA1; HHEX; ATF3; TAL1; NFE2L3; TWIST1; ZBTB16; TP63; HOXA5; YBX3; SP110; SNAI2; TGFB1I1; POU2AF1; ELF3; FOXF2; BASP1; HOXD1; TRIM16; ARNT2; ERBB4; LITAF; TGFB1; NR1H2; IFI16; TFAP2C; ZFPM2; GATA6; CEBPD; MEF2C; ESR1; PSIP1
Down-regulation	103	EZH2; CCNA2; CREB1; ATF1; KDM5B; SOX4; BRCA1; ETV1; HMGB3; MYBL2; MAGED1; HSF2; RBBP4; VEZF1; BRD8; TLE1; BAZ2B; BRD3; E2F6; ID2; SMARCA5; NCOA1; RBM14; CENPF; ATF7IP; KDM5D; SAP130; LEF1; RAN; PTTG1; PIAS3; HMG20A; RYBP; SNW1; NPAT; ARID4A; TULP4; PIAS1; CBX5; MYCL; BLM; HNRNPD; HSBP1; PATZ1; ZNF516; ZNF410; BMI1; PURA; MYB; PMS1; TSC22D4; NAB1; TSC22D2; CREBZF; ZBTB1; HMGN3; MYCN; NR2F1; BATF; ITGB3BP; NCOA6; BATF3; TCF4; DNMT3B; ZBED1; JARID2; ARID4B; RLF; HMGB2; CBX3; TCF12; HOXA11; POLR2A; MAF; NR2F2; MLXIP; DACH1; ING2; BBX; TGIF1; RBL2; SFPQ; ZFP36L2; RHOA; SIX2; SSBP2; AFF1; TCFL5; SERTAD2; CHD7; ASCL1; TOB1; HLTF; FOXC1; SMAD1; SIX1; TXNIP; TOX3; HOXC6; TBL1X; MEIS1; SUV39H1; NFATC3