Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID25981	Jq1-(+)	GSE70138	NEU	Human	24h	3.33uM	EID0086

Response Information :

Types	Number	Response transcription factors
Up-regulation	112	CREG1; TP53; STAT1; CEBPA; IRF8; ZNF124; MYRF; GFI1; CALCOCO1; ECD; RUNX1; AATF; ZNF117; LHX6; HHEX; IKZF1; IRF9; ZNF217; PNRC1; FOXA1; CREBZF; STAT4; NEUROG1; VPS72; BAZ1B; PRDM1; CAMTA1; TGFB1; ACTL6B; DLX4; XBP1; NKX3-1; CBFA2T3; BCL11A; ELF5; DLX2; MYBL1; LYL1; TOB1; ZNF394; ZNF85; NR1H4; TERF2; ELF3; ZFP36L2; KLF13; ZKSCAN1; ETS2; BAZ2A; DACH1; MAF; MNDA; ST18; HMGN3; TRIM24; NEUROD1; MED13; MYCL; MYBL2; NFE2; CCNH; ELK3; CD3D; EGR1; BTAF1; KLF10; DBP; JUP; RUVBL1; AFF1; ZBED2; HOXB2; NFAT5; COPS2; DAXX; HDAC9; NFE2L3; ZNF430; PTRF; CUX1; NFE2L2; TFAP2C; TRIM22; CREB3L2; FOSB; IRF7; OSR2; HLX; DMTF1; ZBTB38; ZNF131; ZNF652; DLX5; RFX5; SSBP2; HLF; FOXC1; NR0B1; BHLHE40; SOX9; ZFPM2; ZBTB20; ZBTB16; GATA6; HOXB6; IFI16; TRIB3; ID1; WT1; IRF6; NR4A2; ESR1
Down-regulation	108	SALL2; HOXA7; SAP18; SMARCB1; ADNP2; NR3C2; TOX; ZNF432; MED7; ZNF468; UBE2L3; TADA3; ZBED4; TSC22D3; ATF1; THAP7; CCNA2; PTTG1; ZZZ3; CHD3; TOPORS; NUP62; ID3; MED15; TTF1; HABP4; NR2E1; NEDD8; MTA1; ZNF274; WHSC1; PKNOX2; TRIM32; TCEA1; PMF1; ZNF226; SREBF2; ETV1; PIAS2; ZFP36L1; EDF1; C1D; HMGB2; TGFB1I1; PPARGC1A; KLF6; ENY2; PSIP1; RFXANK; ZNF593; KLF5; ERBB2; BCL11B; RBFOX2; TBL1X; WWTR1; DNMT3B; ASCL1; NCOA1; KLF7; PUF60; ZFHX4; SMAD2; MECOM; PHF2; ZNF32; SREBF1; FOXO1; ZMYND8; TLE1; ISL1; RXRA; SMAD1; PEX2; HIC2; SETD2; RBPMS; TSC22D2; HDAC1; NKX2-2; SMAD4; TCF7L2; PITX1; TCF12; HIF1A; MSX1; ING3; MEIS1; DDIT3; ATF4; TRIP6; ENO1; PATZ1; HSF2; MXI1; NR1H2; PDLIM1; HOXB7; PEG3; EYA1; NR2F6; HEY1; PIR; BASP1; ZNF281; MED1; PBX1; ZBTB18