Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID25929	Mk-1775	GSE70138	NEU	Human	24h	1.11uM	EID0086

Response Information :

Types	Number	Response transcription factors
Up-regulation	154	IRF8; HHEX; GABPA; ECD; FLI1; BHLHE41; HOXC10; HIPK3; EPAS1; FOXC2; ZNF235; NR0B1; ETV5; ZNF225; IRF2; ZHX2; SKIL; SOX9; SP1; TBX3; NKX2-8; JAK2; MAFB; HOXC4; RARB; GCFC2; PAX8; GATA3; HLF; AFF4; CD3D; TRIM27; IFNB1; ZNF571; EMX1; LHX1; TRIM22; NFATC1; HOXA6; ZNF586; PRRX1; MEOX1; ELF5; ZBTB20; SOX13; MDM2; FOXC1; HOXA2; AGO2; GFI1; NR2F1; ZNF200; THAP10; ANKRD1; HOXD1; TBX21; GATA4; ELK4; E2F4; TAF4B; ZNF10; STAT1; SOX18; PREB; TAF1A; ZNF227; LYL1; TFCP2; NR1H4; MNX1; FOXE1; ZNF14; MNDA; TRPS1; ZNF557; DLX4; ZMIZ2; TAF1C; ETS1; BBX; TLE2; ZSCAN18; PCBD1; CEBPE; BRWD1; IRF9; VGLL1; NFKBIB; IRF1; SLC2A4RG; EN1; HDAC4; MED21; HOXC6; TFAP2C; NR1H3; IRX5; CBFA2T3; PTRF; RFX5; FOXI1; DNAJC2; SOX17; ZBTB38; CBFB; CBX7; ZFP36L2; PPP1R13L; WWP1; TEAD4; ZBED2; AHR; GTF2I; SALL1; KLF9; SPEN; BRD2; HOXB6; SHOX2; ZNF354A; ZBTB16; NFE2L2; TULP4; NR2F2; WWTR1; NKX2-2; DDIT3; TFEC; IKBKAP; HOXB2; BCL6; RERE; LOXL2; IRF6; TP63; ING3; MYBL1; RBPMS; CALR; MYRF; OSR2; DMTF1; GATA6; NKX2-1; ESR1; TULP3; FOXF2; TRIM29; TRIB3; ID1; CEBPB; PIR; NR4A2; MAGED1
Down-regulation	118	PSMD9; SOX4; SREBF1; INSM1; RNF138; TAF10; NUP62; RAN; XRCC6; SIX2; SMARCB1; FLNA; VEZF1; MEIS1; C1QBP; ATF4; TADA3; NEDD8; KLF6; ARID3B; ENY2; HIC2; BATF3; MAFG; WIZ; ZNF432; CBX3; CARHSP1; DDX5; NELFB; KLF7; TCF12; BTG1; TSC22D2; GLI3; DR1; ZNF468; SUMO1; SMARCA5; SOX2; PRKDC; TRIM28; PUF60; MYCBP; RBBP4; DEAF1; E2F3; ZNF24; KDM5B; NFKBIA; IRF7; HDAC2; PITX1; ILF2; EDF1; PCGF2; CRY1; YBX1; SALL2; CREB3L1; TCERG1; FOXO1; ASCL1; YWHAB; NPAS2; COPS2; TOX3; PHF20; ZNF532; NONO; UBE2I; BMI1; HTATIP2; REPIN1; SMARCE1; NCOA2; EYA2; ZFHX4; PQBP1; SOX11; SCAND1; ZMYND8; ASH2L; HMGB3; MXI1; FOXG1; FOXN3; ENO1; LEF1; ELF4; ZNF302; TBL1X; ABL1; MED1; TCEA1; PCGF3; LPIN2; EYA1; ZNF3; RBM39; TCEB2; NR1H2; ZNF281; RBPJ; TWIST1; VGLL4; ID3; SMAD4; TGFB1I1; TCF4; SATB1; TBX2; SMARCD3; MSX1; PEG3; BASP1; EMX2; MECOM