Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID25890	Rucaparib	GSE70138	NEU	Human	24h	0.04uM	EID0085

Response Information :

Types	Number	Response transcription factors
Up-regulation	109	MEF2C; NR1I2; FOSB; SCRT1; TAF4B; ZNF154; ETV6; JAK2; NFATC1; DOT1L; PRDM2; KLF4; OVOL2; GATA1; IRF8; MYNN; ZNF507; E2F2; KLF11; STAT1; PSMC3; ELF5; SOX13; VGLL1; GATA4; FOXE1; HOXC5; ZNF224; PGR; ZNF552; SRY; MAFF; ZNF816; SOX18; NR0B1; DLX5; FHL2; ETS1; ZNF215; THRB; RXRG; SOX17; TDP2; REL; RUNX1; ISL1; SOX10; NKX3-1; IFNB1; KLF2; SIAH2; LHX3; LHX6; IRF2; HHEX; TRIM16; SKIL; ECD; TLE2; HEY2; ELF3; NR4A2; NR4A3; HOXD1; MYCL; CBX7; PPP1R13L; WNT4; TAL1; OSR2; ZNF264; NPAS2; GATA6; TEAD4; IRF6; SPIB; IRF9; FOXN3; CBFA2T3; CEBPB; ZHX2; BCL11A; PDLIM1; TGFB1; AHR; PRRX1; IFI16; STAT6; HDAC9; EHF; PIR; ZBTB20; NR1H2; TBX3; HOXA5; PTRF; EYA2; TRIM22; ATF3; CRYM; SATB2; DACH1; LMCD1; NR2F6; BHLHE41; TRIB3; ESR1; MYBL1; PSIP1
Down-regulation	83	HIF1A; BRD8; RYBP; THAP4; TAF12; CBX3; SOX4; TCEB2; CBX5; RBPJ; E2F3; ASH2L; SMARCD3; ZNF281; TBL1X; ZNF3; KAT6A; KAT8; ZBED1; MAGED1; RNF4; ZNF266; NONO; PCGF3; CUX1; SAP18; ZBTB1; PCGF2; PMF1; TRIM32; BASP1; LEF1; NCOR2; ZMYM2; SMARCE1; SAP30; SMARCA1; APEX1; FOXD1; TAF1D; PURA; NCOA4; BRD3; TWIST1; HIC2; SMARCA4; PSPC1; BCLAF1; ADNP; ZIC1; ZNF432; HDAC2; SSBP2; NEUROD1; LITAF; ING2; RORA; HOXB6; NUP62; ZBTB18; RBBP4; TFEC; KDM5D; MNT; ZNF217; ZNF711; FOXJ3; NAB1; CHD7; ENO1; AFF1; JARID2; ASCL1; TOX3; MECOM; ZNF91; ZMIZ1; TLE4; MYRF; HMGB3; DAXX; ID4; WT1