Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID25773	Olaparib	GSE70138	NEU	Human	24h	10uM	EID0085

Response Information :

Types	Number	Response transcription factors
Up-regulation	75	GATA3; MBD2; NKX3-2; RUNX1; TGS1; CUX1; CCNE1; HOXD9; TGFB1; ZNF467; SP140L; ZNF444; MDM2; TGIF1; AES; KLF13; MAZ; NFIC; AIP; CBX6; MEF2A; TAF4; LEF1; MEOX1; SMAD4; ZNF107; HOXB2; ERBB4; KLF7; ECD; PBXIP1; ELF4; BCL6; RORA; HES1; KLF10; TGFB1I1; SHOX2; TRIM22; ETS1; WNT4; FOXD1; MYBL1; SIAH2; SMAD1; CAMTA2; NCOA1; MYBL2; KLF2; TBX3; NPAS2; IFI16; IRF7; FOS; RBBP8; STAT6; ZSCAN31; ATN1; LMCD1; PAWR; AEBP1; POU2AF1; TWIST1; LOXL2; ZNF652; NFE2L2; HOXB7; TCF21; TOX; TLE4; DACH1; MAFB; TOB1; CHD7; TRIB3
Down-regulation	110	PARP1; SSRP1; TEAD1; PBX1; LITAF; ZNF350; PHF20; ZNF510; ZNF614; CBX5; INSM1; ZNF432; NEUROD1; ZNF813; BTAF1; AFF1; ZNF175; NFX1; RBBP4; NHLH2; ZNF562; TFCP2; ZNF268; SATB2; TAF10; RNF10; ZNF124; CNOT1; HOXB13; KDM5D; ZSCAN9; ZNF266; ZBED1; ZNF573; RBM39; TBL1XR1; HSBP1; FUBP1; EZH2; ZNF304; ZNF93; L3MBTL1; SMAD6; ZNF544; SAP18; MED23; SMARCA2; ZNF3; RFX7; EGR3; TBP; TAF9B; ZNF468; TSC22D1; MED24; NR1D2; EP400; TOX3; HBP1; FOXO3; PHIP; ZNF302; SOX9; JUP; EHF; TAF1D; NFIB; GTF2IRD1; PITX1; PFDN5; PLAGL1; EDF1; BRD3; HIPK3; NCOA6; DEAF1; ABL1; ERBB2; TRIM16; ZNF331; BCL11A; FOXG1; CERS6; ZMYND8; MED1; PEG3; CENPF; ERG; SMARCA1; BRD8; BTF3; MYCN; HMGB3; CTNNB1; RUNX3; FOXJ3; NANOG; ASCL1; MYT1L; EMX2; SOX11; HMGN3; NONO; SIX2; BASP1; RBPJ; HEY1; BHLHE41; JARID2; TXNIP