Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID25692 Gsk-1059615 GSE70138 ASC Human 24h 3.33uM EID0069
Types Number Response transcription factors
Up-regulation 109 TBX2; MNAT1; CBX7; ING1; HMGA2; UBE2B; HBP1; RERE; EZH1; FOXO4; MEOX2; FOXG1; MAFF; GTF2IRD1; ATF4; ZNF419; CALCOCO1; TP63; CREM; EMX2; ZNF587; TGIF1; TULP4; DDIT3; DACH1; ZBED1; HCFC2; ING3; JUP; TDRD3; PATZ1; ELF3; ZNF32; TSC22D4; ZMIZ2; JUNB; TOB1; SAP18; FOXN3; SOX13; ZNF222; ZNF586; POU4F1; NFATC3; ZNF304; ARNTL; RXRA; ZNF263; EHMT2; ZSCAN16; HOXB7; KLF9; SIX1; ZNF134; CREBL2; NCOA1; KLF5; HOXA1; MECOM; ZNF394; SMAD7; PHIP; CBFA2T2; ZNF551; TRIM28; ZNF160; OVOL2; BAZ2B; TSC22D1; SALL2; CEBPA; MYCL; ZNF329; HEY1; TXNIP; ERG; ARID4A; BCL11B; DLX5; ZNF189; BRD3; ZNF165; ZNF721; ZNF211; SIM2; TDP2; SMARCA2; HMGA1; BCL11A; SATB2; SOX17; PLAG1; NR1D2; ZMYND8; ABL1; FOXC1; ZNF331; RORA; PAX6; ZBTB20; NANOG; TOX; INSM1; ZEB2; DAXX; ZIC1; HOXD1; ID1; HOXC6
Down-regulation 37 AR; TGFB1I1; BRD4; NFIC; CITED1; HMG20A; ZNF146; TRIM22; BHLHE40; HAND1; ZNF274; TCERG1; ZNF532; MEIS1; POU2AF1; WWC1; ENO1; ESRRG; FOSL1; SUB1; WT1; ZNF12; CD3D; ZNF512B; ASH2L; SOX2; LMCD1; ZBED2; PITX1; CTBP2; SIX2; MNDA; HLTF; ESR1; ZFPM2; MEIS2; BASP1