Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID25619 Jq1-(+) GSE70138 ASC Human 24h 0.04uM EID0069
Types Number Response transcription factors
Up-regulation 45 NFATC1; SSBP3; MED23; PROX1; YBX3; LYL1; OVOL1; BCL11A; GFI1; POU4F1; SPDEF; NR1H3; ERG; CBFA2T3; AES; INSM1; KDM5B; ARID4B; BCLAF1; CNOT6; KAT8; PHIP; PFDN5; TXNIP; MYB; INSR; SREBF1; ZNF721; ENO1; DLX5; BTG1; TFEC; HSBP1; SMAD7; KLF9; TBX3; TOX3; PURA; ID2; ZBTB18; HOXC6; SOX9; MAF; KDM5D; BASP1
Down-regulation 52 CREG1; ZKSCAN5; ZZZ3; TEAD3; RBBP8; NR2F6; SRF; AHR; SALL1; SMARCD3; MECOM; PLAGL2; HOXA1; TRIM22; ZFP36L1; DDIT3; MEIS2; STAT6; MEOX2; CALR; SP140L; FOSL2; SATB2; ERBB4; TDP2; PBX1; TCF21; CHD7; AFF1; TWIST1; RXRA; EGR2; MEIS1; TRIP6; MNDA; ZNF423; FOXF1; EGR3; TFAP2A; ISL1; IFI16; ZNF217; FOXF2; HOXB6; ZNF232; VPS72; ZFPM2; TOX; MYBL1; WT1; HOXB2; TRIB3