Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID25614	Jq1-(+)	GSE70138	ASC	Human	24h	10uM	EID0069

Response Information :

Types	Number	Response transcription factors
Up-regulation	119	MTF2; CHD4; DBP; GATA3; TAF12; ZBTB43; CHD1; PHIP; ETS2; TAF1; IRF4; PGR; TOB1; BRD2; ID2; MED23; PIAS1; SMARCA5; ORC2; PNRC1; ENO1; NFIC; WWP1; NR4A1; REL; THRA; MXD1; DPF2; AFF1; NR2C1; BTG1; KLF9; MYB; COPS2; LEF1; KMT2A; ARID1A; NLK; RCOR1; MXD4; HMG20A; TXNIP; HINFP; HBP1; DNMT3B; TOPORS; BAZ2A; CCNT1; UBE2B; ZNF516; SSBP3; KLF10; GATAD2A; ARNTL; RORA; TGIF1; ZBTB18; CDK9; RLF; FOXL2; POLR2A; SOX4; MED24; PIAS3; CBFA2T3; MITF; RYBP; BCLAF1; INSM1; KAT7; ARID4A; TLE1; ZNF329; HSF2; INSR; CTR9; ZSCAN31; CUX1; ZMIZ1; ID1; RNF141; PPARGC1A; MED1; HMBOX1; ERG; PAWR; IRX5; FOXA2; DLX5; TOX3; EMX2; BASP1; TRPS1; JUNB; ASCL1; ZNF189; OSR2; CTBP2; ZNF721; BAZ2B; ZBTB16; EGR3; CHD7; SATB2; NFAT5; NR5A2; PIR; HTATIP2; PLAGL1; LITAF; ZFP36L2; DNAJC1; NR1D2; MSX1; PBX3; MAF; KLF5; HMG20B; KLF2
Down-regulation	124	EYA1; IFI16; HOXD11; CEBPA; CREG1; XBP1; MEOX1; ATF4; ALX1; ECD; ZNF133; TRAK1; HOXB7; FHL2; ZNF32; TEAD3; ATF1; POLR3F; GTF2IRD1; SMARCD3; PBX1; PKNOX2; RARB; SUB1; DDIT3; ZNF354A; ZNF337; DEK; TRIM27; SRF; TRIM22; ETV7; HDAC9; MAX; GTF3A; PCGF1; CEBPG; PITX1; ELF5; HOXC4; STAT2; SP140L; RBFOX2; NPM1; FOSL1; TFCP2; STAT6; POU3F2; BTF3; FOXC1; COPS5; MED27; FOXM1; SOX11; HOXB2; TCERG1; ZNF580; NPAS2; CD3D; TLE2; DDX17; NR2F1; NR0B1; FOXF2; ANKRD1; ARL2BP; PCGF3; PTTG1; CENPF; ZNF532; SP110; VPS72; POU2AF1; NR1H3; FLI1; WT1; ZNF512B; CBX6; TCF7L1; ZBED2; NFATC4; ZNF529; HMGB1; ARNT2; SIM2; MYBL1; SNAI2; PITX2; HEY1; ZNF232; SLC2A4RG; BHLHE41; PEG3; NR2F6; HIRA; TRIB3; ZNF544; TCEA1; ISL1; NCOA4; ZNF239; EGR2; MEIS2; ZNF91; SIX2; ILF2; SIX1; TRIM29; NKX2-2; TTF2; TOX; HOXD1; CCNE1; TGIF2; EYA2; TFAP2C; MECOM; EHF; HOXB6; ST18; ZFPM2; NFE2L3; MAGED1; ZNF586