Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID25593 Olaparib GSE70138 ASC Human 24h 0.37uM EID0069
Types Number Response transcription factors
Up-regulation 25 TBL1XR1; LYL1; AATF; CRYM; ZNF721; CALR; ZBTB20; FOXC1; NFATC3; DDIT3; CITED1; MDM4; INSM1; RNF141; DACH1; HDAC9; NFIB; ASCL1; NR1D2; TXNIP; BHLHE41; SOX9; MYRF; ZEB2; KLF2
Down-regulation 28 YBX3; ETS2; MAFB; PAWR; TSC22D1; SATB2; ZNF12; FOXO1; BCL6; AR; TEAD4; ID3; HEY1; IRF8; ZNF281; EGR3; TLE4; ID1; IFI16; FOXG1; SMAD1; ZFP36L1; FOXF1; TBX3; LEF1; DLX2; HOXB6; TRIB3