Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID25565 Gsk-461364 GSE70138 ASC Human 24h 0.37uM EID0069
Types Number Response transcription factors
Up-regulation 50 JUN; TGIF1; ZNF768; PTRF; TRIP4; BCOR; HIPK3; ZNF22; HEY2; FOXC1; SALL1; POLR2A; TCF7L1; NFIB; HLX; AFF1; SMAD6; TBX3; TLE4; HLF; TRPS1; ERG; PHF20; HBP1; EPAS1; PPARGC1A; PTTG1; AHR; NFATC3; BRD3; SIAH2; ID4; TAL1; EGR3; ZEB2; RORA; MXI1; MYB; HTATIP2; FOXG1; KLF9; ZBED2; HOXC6; NR1D2; TOX; NR2F1; ZBTB18; CITED2; MAGED1; NR2F2
Down-regulation 25 GTF2F1; CAMTA1; KLF4; BHLHE41; CREBL2; HOXB7; ETS2; ZNF430; ZNF44; EYA2; ZNF91; REL; IFI16; BAZ1A; ZMYND8; SNAI2; MEIS1; E2F5; PITX1; NFE2L3; ESR1; TGFB1; MECOM; FOXF2; MEIS2