Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID25561	Mitoxantrone	GSE70138	ASC	Human	24h	10uM	EID0069

Response Information :

Types	Number	Response transcription factors
Up-regulation	134	NFATC1; LHX6; MXD4; EED; CREBL2; NFKBIB; HOXC5; HOXC4; NHLH1; ZNF783; RSF1; DLX4; SHOX; CALCOCO1; CREBZF; OVOL2; HOXC11; ZNF835; TFEC; TCF4; RING1; ZNF532; CLOCK; E2F2; TBX19; STAT2; ID4; ELK4; DACH1; GRHL2; E2F1; MBD1; POU2F2; BCL11A; CBX7; ING4; ZNF672; ZNF107; L3MBTL1; CSDE1; SFMBT1; PEX2; FOXN3; ZNF83; ARNTL2; ZNF816; KDM5A; TLE2; SIM2; ZNF711; INSM1; IRF8; ZBTB17; PRMT2; ZNF117; CDK2; SRCAP; ZNF136; NR0B2; CTNNB1; ESRRG; ZBED2; ZNF611; MZF1; DDX17; CREB3L2; FOXM1; NR1H3; ZBTB44; PRDM2; ZMYND11; MBD2; ZNF492; ZKSCAN7; SOHLH2; UBE2L3; IRF6; ZNF701; SND1; MYCBP; MYCL; MYBL1; PRRX1; ZNF22; ACTL6A; WDR77; ZNF354A; PSIP1; KDM5C; PRDM12; ZNF224; YBX1; PLAGL1; KAT2B; BCL6; WNT4; ZNF75D; ZNF165; REPIN1; VGLL1; HMGN3; CALR; ZNF529; ZNF721; MED14; TRPS1; RBBP8; TCF3; EHF; HSBP1; MEIS1; TTF2; RFX5; SOX17; EGR2; ERBB4; TAL1; VDR; CCNE1; ZNF512B; E2F5; TWIST1; PAX6; ZNF551; NR5A2; DLX2; MEIS2; GATA6; TFAP2A; ID1; HLTF; TXNIP; TOX; HOXC6
Down-regulation	128	CDK7; MYC; NFIL3; FHL2; NFKBIA; CEBPB; ZBTB11; FOXO3; DDIT3; CCDC59; RREB1; FOSL1; RLF; ADNP; TBPL1; PUF60; CEBPZ; SMAD1; HOXD10; CHD1; AATF; RNF111; GTF2IRD1; PCGF1; TLE1; SETD2; FOXJ3; XBP1; CDC5L; PHF20; RBM39; NUP62; ZNF217; NCOA3; TBP; RORA; NFKB1; MLX; CTCF; SCAND1; SALL1; BRD2; KLF4; FOXO1; MAX; RBPMS; RAN; PCGF2; MED6; TOB1; ZBTB16; VEZF1; BCLAF1; MGA; SMARCE1; RYBP; YWHAB; BTF3; ARNTL; CRYM; CITED1; SMAD3; NRIP1; UBE2I; AFF1; KLF6; RNF138; NCOA6; ZBTB1; CEBPD; SAP30; YEATS2; NPAS2; ZNF12; TGIF1; IKBKAP; ATF4; BRPF1; SREBF1; MED1; CCNA2; HNRNPD; ELF1; CHD7; JARID2; FOXA2; PQBP1; ETV5; ZFP36L1; CREB3L1; LOXL2; DNMT3B; BTG1; KLF2; SNAI2; ZMYND8; MED17; BCL11B; TSC22D1; NFE2L1; TBL1X; ZNF281; HOXA5; CENPF; JUND; PIR; TSC22D2; ARID4B; PBX1; EGR3; KLF9; ZBTB38; HOXB6; MNDA; CITED2; IFI16; CTR9; EDF1; MAGED1; KDM5B; CEBPA; HOXB7; ATF3; TOX3; HOXB2; BASP1; PEG3; TFAP2C