Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID25557 Mk-1775 GSE70138 ASC Human 24h 1.11uM EID0069
Types Number Response transcription factors
Up-regulation 64 NR4A1; MLLT10; TOPORS; ELF3; MNDA; MYCL; ZNF426; FOSL2; JAK2; TCF12; EP300; YEATS4; WT1; TRIM29; PAWR; ELF5; CREB3; YAP1; MEIS1; NFATC3; ZNF268; SOX17; EGR3; NR4A2; NFE2L2; TFEC; TP63; ID4; ZBED4; ZNF652; IRF8; ZNF551; KLF6; MED14; CITED2; REL; ATF3; E2F8; PEG3; MYCN; EMX2; NFE2L3; HIC2; ZNF304; FOXM1; TFAP2A; ZFP36L1; ZNF573; FOSB; RBBP8; TFAP2C; TCF21; PSMC3; ZNF217; BNC2; ATF5; TBX3; IRF6; BHLHE41; ZBED2; TRIB3; ESR1; MEIS2; DAXX
Down-regulation 24 USP22; SSBP2; NPM1; SMARCA1; TXNIP; ZNF274; HEY1; ING3; CTNNB1; PTTG1; EYA1; MBD2; KDM5D; YBX1; CBFB; RBPMS; MAGED1; IRX5; TGFB1; ELK3; PITX1; ZBTB38; MAF; HOXC6