Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID25548 Vorinostat GSE70138 ASC Human 24h 10uM EID0069
Types Number Response transcription factors
Up-regulation 41 HDAC2; SOX4; E2F2; HEY2; ADRB2; ZNF226; NR3C2; BBX; RCOR1; ID2; JARID2; FOXO4; SMARCD3; TCFL5; IRF4; RUVBL2; SOX10; WWTR1; CRY1; PTTG1; PBX1; SALL2; SATB2; CTR9; NR4A2; ASCL1; BCL11B; MNAT1; SIX1; TOX3; MXI1; HLTF; ZNF331; PSIP1; HMG20B; ZBTB18; ID3; BASP1; ZBED2; SOX11; PDLIM1
Down-regulation 39 XBP1; FOXM1; ATF5; CEBPG; ZBED1; KLF4; ELF3; FOSL1; PCBD1; TRIM29; TRIM22; ARL2BP; POU2AF1; HMGA2; BHLHE40; SP140L; VGLL4; CENPF; NKX3-1; NCOA2; TGFB1I1; CEBPA; TP53; NR2F6; EMX2; INSR; ZNF264; HMGB2; ZNF512B; ZNF423; TRIP6; TULP3; FOXF2; HOXB2; KLF2; VPS72; MEIS2; ESR1; ARNT2