Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID25518 Belinostat GSE70138 ASC Human 24h 10uM EID0068
Types Number Response transcription factors
Up-regulation 83 RUVBL1; COPS5; MYBL1; SUPT4H1; ZBED2; HDAC1; DLX4; TERF1; WWC1; NCOA3; CDK2; NFE2L3; CCNC; CHD7; SUPT6H; MNAT1; PRKDC; GTF2F1; SUPT3H; TCEA1; E2F5; BCL3; JUND; ERF; FOXK2; PKNOX2; SSX1; CBX7; SMARCD3; HIRA; GATAD2A; HDAC9; RLF; MLXIP; BACH2; NEDD8; RBBP8; HHEX; ID2; LEF1; ZNF217; MYCL; SPEN; SSBP2; NR2F1; SOX10; TAF4B; TAF6; TFAP2A; NFATC4; GMNN; NKX2-1; ID4; TAL1; SALL2; TGFB1; DLX2; TGIF2; PITX2; WT1; BBX; POU4F1; TFAP2C; HMG20B; PTTG1; POU2AF1; ZNF281; MNDA; HEY2; SOX9; MXI1; ETS1; PAWR; PBX1; ATF3; MYBL2; TOX3; DAXX; PBX3; BHLHE41; IFI16; ZHX2; ID1
Down-regulation 89 CEBPA; PCBD1; HDAC6; STAT5B; XBP1; RBPMS; PPARG; USP22; CCNA2; ZBED1; TP53; IRF5; ATF1; ADNP; TRIM22; STAT5A; ZNF432; PIR; TGIF1; NR1H3; EWSR1; ZZZ3; SP100; STAT6; PATZ1; TRIM28; MSC; ZFP64; BAZ2B; ING3; NFKBIA; C1D; RRN3; RORA; TFDP1; HMGB2; PMF1; BCLAF1; AR; ATF5; POLR2A; TMF1; MED1; SP3; HTATIP2; NFKB1; PLAGL1; MEIS1; ZBTB38; PHF8; SIAH2; SMARCA2; PHF2; CHD9; SFPQ; ERG; NFIB; PBRM1; ZBTB20; ZBTB43; HMGN3; HIPK3; ERBB2; KLF11; RNF6; ZNF189; ZEB2; MEOX2; BASP1; MXD4; SALL1; BTG1; BACH1; TBL1X; HMGA2; KDM5D; KLF4; EYA2; TRIP6; TRIM29; TGFB1I1; HOXC6; MYB; TXNIP; KLF2; MAFB; NR1D2; CREB1; E2F2