Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID25512 Rucaparib GSE70138 ASC Human 24h 10uM EID0068
Types Number Response transcription factors
Up-regulation 34 CEBPZ; GTF2I; ZIC1; ZBTB38; GATA3; MKL2; PSIP1; SHOX2; HTATIP2; PAX5; CNOT3; BASP1; KLF4; CARHSP1; MYCN; DNAJC2; CREB1; ZFP36L2; SMAD1; EMX2; KLF10; KLF9; KLF6; PAX6; BCL11A; TULP3; BCLAF1; SOX9; PLAGL1; INSM1; ZKSCAN1; TXNIP; FLNA; ETS2
Down-regulation 57 NR1H3; RSF1; SOX2; COPS5; ZNF184; TBL1XR1; TRAF6; SMAD6; ZNF7; PKNOX2; NR0B1; ZNF532; PRKDC; CD3D; HOXD11; ZNF112; BCL10; CREB3L2; WT1; L3MBTL1; LPIN2; HIVEP1; ZBTB44; ZNF22; NR4A2; NFIC; TCF21; TFDP2; MNDA; TCF12; CHD7; GFI1; EYA1; TAL1; SOX10; ID3; HDAC4; NKX3-1; NKX2-1; ZNF195; SREBF1; SSX1; NFAT5; ANKRD1; ASCL1; NR1H2; TGFB1I1; ZBTB16; IFI16; ZBTB20; STAT4; ZFPM2; TFAP2C; SNAI2; BHLHE41; GATA2; E2F2