Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID25504 Gsk-1059615 GSE70138 ASC Human 24h 0.12uM EID0068
Types Number Response transcription factors
Up-regulation 356 CEBPZ; GLI2; STAT2; ZNF286A; NOCT; PSMC3; MED25; E2F5; ZNF264; ZNF586; MYCN; FOXN2; SOX9; MYCL; ZNF544; ZIC3; AFF3; PPRC1; ZBTB3; CREB5; TCEA2; SIX6; MYBL1; KLF13; KLF7; KLF3; NFIX; ZNF117; TFAP2A; RELB; HMBOX1; ZNF573; FOXA2; RBBP8; RAD21; ASH1L; ZNF529; HIF3A; ZNF345; ZNF440; TBX5; RB1; ID1; CSDC2; POU3F2; POU6F2; KLF6; NR2C2; SUPT6H; TAF9B; TFDP2; ZNF273; ZNF177; ZNF223; BRDT; CALCOCO1; FOXE3; ETV3; IKZF2; HIPK2; ZNF415; ZNF24; TRPS1; THRB; ZNF749; ZNF665; ETS1; EN1; ZNF675; ZNF682; PIAS4; TULP2; TAF4B; CARF; ILF2; ZSCAN18; ZNF471; VENTX; ADRB2; BARX1; HOXB2; MED20; ZNF132; BCL11A; DCC; ARNTL2; LIN28A; ZNF221; NFE2L3; ZNF154; SPI1; HOXD12; ZXDB; THRAP3; NFKB2; ZNF654; VPS72; ZNF780B; ZNF350; ZBED2; EMX1; ZNF232; TEF; SUMO1; POU2F1; HESX1; PAX1; SOHLH2; TCF21; FEZF2; ZNF549; PRDM13; ZBTB44; ZNF225; ZNF253; FOXH1; NEUROG3; ZNF214; SCAI; CNOT3; MYEF2; ZNF550; NR2F6; ZNF835; ZNF667; SPEN; PRRX1; TBR1; NKX3-2; MSX2; ZNF814; IKZF3; TAF5; BACH2; ZNF136; ZNF141; HDGF; ZNF571; ZSCAN9; PRDM2; PPARA; IRF6; GMEB1; HOXA6; MDM4; PRDM14; PBX3; ZNF711; SOX14; TCEA1; POLR3C; NFATC4; ERF; FOXG1; ZNF41; ZNF254; SUV39H2; THAP9; ZNF224; GSC2; PCGF3; ZNF235; NEUROD1; KDM5C; CBFA2T2; RFX3; NPAS2; ZNF362; ZNF81; HOXB5; GCM2; UTF1; ZNF304; POU1F1; JUN; ZNF562; LHX2; ZFP69B; NANOG; NEUROG2; IRF9; IRX4; GTF2I; DLX2; PNRC1; ZNF480; TFCP2L1; MAPK8IP1; HOXA2; ZNF239; TP73; HIC1; SCRT1; PAXBP1; MLLT1; ZNF426; ZNF74; ZNF391; FOXF2; POU3F3; ZNF44; NAB2; REL; GBX2; ONECUT1; SRCAP; KLF5; ATN1; ZNF701; HNF4G; VHL; PHIP; PBX1; PRDM9; CUX2; ZNF611; ZNF770; PAX4; ZNF329; ZNF460; ZNF695; ZNF80; ZNF257; ELF5; ZNF195; CHD2; BCL6; ZKSCAN8; ZBTB6; BNC1; ZNF407; ZNF155; CARM1; TGIF1; FOXD3; PRDM12; ZNF674; YEATS4; HNF1B; ZNF75D; POU2F3; ASCL2; SOX1; GCFC2; FOXN1; FOXF1; ZNF334; CHD8; PLAGL1; POU4F3; MAML3; NAB1; SIX3; ZEB1; ID4; ZNF222; DNMT1; HBP1; TBX1; SOX21; TCF7L2; ZNF493; PPP1R13L; ZNF500; ZNF507; MYT1; NKX2-1; TLX3; WWC1; ZNF211; ZNF43; TCF4; ZNF551; CTBP2; SPDEF; VGLL1; BACH1; HOXD3; DOT1L; NEUROG1; PRDM1; GFI1B; MYRF; TULP3; HOXB13; OVOL2; PEG3; ERBB4; SUZ12; HMGB1; MEOX1; ATOH1; NR1H4; SRY; ZNF180; MYBL2; RARG; ST18; ZNF227; NKX2-2; SOX18; HIVEP2; RFX2; GRHL2; GATA1; BRWD1; HOXD1; INSM1; E2F2; TAL1; PAX6; ZNF91; ZNF83; SERTAD2; ZBTB20; BRCA2; ZNF217; AEBP1; RBL1; LMCD1; LHX3; FOXM1; ZNF623; TRIM29; OLIG2; HOXB6; ZNF10; BBX; KLF4; NFE2; TGIF2; OVOL1; RBPJ; SALL2; ARNT2; GMNN; TDP2; SPIB; ELF3; SHOX2; EHF; HMGB3; CALR; DLX5; ZNF331; PAWR; ZBTB38; TOX; WT1; CREB1; ID3; GATA6; ZHX2; ZIC1; TXNIP; NFATC3
Down-regulation 82 PIR; SAP30; SMARCA2; DDIT3; PSIP1; CREG1; PCGF2; C1D; RRN3; ZMYND8; HTATIP2; UBP1; RBPMS; MLXIP; BCL10; NR4A2; MEF2A; ITGB3BP; ZNF593; CCDC59; FLNA; TCERG1; STAT5A; ENY2; BASP1; SMAD3; PSPC1; MYCBP; TCF25; HIPK1; TRIM22; SOX4; RNF6; PHF8; PARP1; RBM14; TGFB1I1; PPARG; ZEB2; NEDD8; MBD2; SMAD2; TBL1X; NR2F2; ZMYM2; HSF2; PHF1; NR1H3; MED6; HOXB7; PTRF; BAZ1A; HDAC1; CERS6; AFF1; PTTG1; YWHAB; MAFB; TOB1; ARID4A; ELK3; BMI1; EDF1; ELF1; KLF2; TRIP6; KDM5D; ATF4; HOXC6; JARID2; EYA1; UBE2B; EYA2; AHR; MLX; MED1; MSX1; ID2; MYT1L; CITED2; IFI16; BTG1