Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID25478 Bix-01294 GSE70138 ASC Human 24h 10uM EID0068
Types Number Response transcription factors
Up-regulation 39 TBL1XR1; SUPT5H; WWC1; BHLHE41; SMARCA5; FOXK2; GTF2IRD1; TRIP6; HOXB13; KLF13; PLAGL2; KLF1; TFAM; SOX9; RBBP8; ZNF165; NR1H3; DEAF1; SREBF1; TSC22D1; KLF6; ETS2; ZBED2; SMARCD3; E2F8; MYB; HTATIP2; ERBB4; YWHAB; TAL1; ETS1; CRYM; MEIS1; KLF5; HOXD1; WT1; PBX1; ID4; EHF
Down-regulation 69 NR2F6; TLE1; MYCBP; ZMIZ2; CDYL; RORA; TRAK1; AES; VGLL4; KAT2B; ADNP; DEK; BCL3; RBBP7; HDAC1; HMG20B; ZFP37; VEZF1; NR0B2; SP140; ABL1; PIR; ELF5; HOXA11; ELF1; PEG3; SMAD3; ZNF529; SIAH2; POU4F1; TCF7; SERTAD2; TRIM22; TRIM32; PRRX1; BAZ1A; TBL1X; ZNF107; JARID2; RFX5; FOXC1; SAP30; DNAJC1; GTF3A; ZBTB1; MAGED1; FOXE1; BMI1; ZEB1; IRF1; SPIB; HEY1; HEY2; TRPS1; KLF2; KDM5D; MYBL1; ZNF91; NR4A2; TOX3; HMGA1; GATA2; LEF1; TXNIP; MAFB; NR2F2; E2F2; CREB1; RELB