Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID25457	Vorinostat	GSE70138	ASC	Human	24h	3.33uM	EID0068

Response Information :

Types	Number	Response transcription factors
Up-regulation	115	EGR2; EGR3; KDM5A; AR; NAB1; MAZ; KDM4A; RELB; POU4F1; NR1H3; BRD4; CASZ1; ARID5A; NFIX; TERF2; ERF; ZBTB17; EGR4; CIR1; NR3C1; BRD2; HOXD9; DYRK1B; BHLHE41; NR1I2; RELA; ZNF212; POU4F2; PRKDC; PKNOX1; ZNF358; DMRT1; MAPK8IP1; ZIC1; NEUROG1; SOX9; ERG; SOX5; TFEB; IRF1; CAPN15; IKBKAP; CHD3; ZNF112; NR5A2; HR; SAP18; MED16; NRBF2; ZNF281; KMT2D; NAB2; NEUROD2; NKX3-1; SOX12; THRA; ZSCAN16; SIM2; TCF7; DACH1; NPAS2; CBX5; CARF; CHD8; NFIB; ZNF22; MLLT1; CUX2; ID4; HOXB13; BNC1; MEIS1; FOSB; NR2F1; KLF13; ZNF160; HNF4G; IRX4; ZNF721; ZNF189; ARNTL2; OVOL1; WT1; TFEC; BASP1; PGR; TP63; NKX2-2; KLF5; ZBED2; KLF7; NFKB1; EN2; SMARCA1; TRPS1; SOX11; SMAD1; WWTR1; PBXIP1; CREB1; REL; KLF6; MED21; SOX17; TCF4; RUNX3; TGFB1; PEG3; TULP3; HOXD1; YBX3; ESR1; DAXX; MYB; IRF6
Down-regulation	80	NR2F6; HHEX; CREB3L2; CITED2; MLXIP; CREG1; ZNF14; OSR2; TRIM28; SIX2; IKZF5; RNF111; HNRNPD; NFYA; SIM1; TGIF1; THAP11; TRAK1; HMGB2; PIR; BATF3; CBFB; AIP; FOXK2; ZNF217; IRF4; IRF3; HTATIP2; HIPK1; PAXBP1; HSF2; ISL1; ZNF468; VGLL4; KLF2; TRIM24; DNMT3B; CRY1; SATB2; TTF1; ATF5; RNF138; NR2F2; CHD1; CCNE1; FUBP1; CALR; RUNX1; MLX; MITF; DDIT3; AEBP1; BMI1; HIC2; ZBTB1; MEIS2; RBBP4; CREM; ID2; KAT2B; AFF1; NFE2; UBE2B; SUB1; LITAF; POU2AF1; PITX1; LIN28A; MYRF; TCF7L2; ZNF652; HLTF; HOXC10; HOXC6; PBX3; TXNIP; TOX3; NR1D2; IKZF1; E2F2