Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID25451 Gsk-j4 GSE70138 ASC Human 24h 10uM EID0068
Types Number Response transcription factors
Up-regulation 111 SUV39H1; TERF2; E2F1; PHOX2B; SP100; HOXB2; CBX2; HAND1; PHOX2A; CREB3L2; MXD3; CITED1; PRDM12; TLX2; FOXI1; FOXK2; FOXH1; SIX3; BHLHE41; ZNF629; GBX1; ASH2L; HOXA6; MBD3; TBX2; MAPK8IP1; PRRX2; DLX4; PAX1; CEBPE; CIITA; SNAI1; EMX1; HNF4A; AR; HOXB1; TULP2; CDX4; FOXO1; THRB; NFATC3; MBD2; PROP1; GBX2; GFI1; E4F1; TAF7; NFE2; GATA1; MLLT1; TCF12; SCRT1; POU4F1; ALX4; CHD2; VAX2; TP73; RORC; ZBED1; HOXC8; KLF15; ZBED2; SP140L; ARNTL2; KLF1; RFX1; PRDM2; EYA1; CBFA2T2; EMX2; SPDEF; NR1H4; TCF4; E2F2; MXI1; MYCL; HOXB7; TLX3; ZEB1; SOX21; ELF5; CERS4; SRY; MED24; RFX2; VGLL1; OVOL1; IL16; HOXB6; KLF13; ZFPM2; TAL1; PITX2; NANOG; TFAP2C; SSX1; WNT4; MEIS2; SIX1; EYA2; EGR2; TRIM29; ATF3; INSR; IFI16; ZBTB20; OLIG2; IRF6; GATA6; EHF; ESR1
Down-regulation 42 NCOR2; CTNNB1; RBBP4; ZKSCAN5; TGIF1; FLNA; CRY1; HMGN3; RBPMS; ZNF281; WWTR1; ZIC1; ZNF468; ZNF529; ZMYND11; SP110; HTATIP2; DNMT3B; NKX2-2; TAF9B; NFIB; TGFB1; RNF4; ID1; YWHAB; LEF1; BCL11B; ZNF587; SHOX2; KDM5D; LITAF; JARID2; TSC22D1; IRF7; HMGB3; ETS2; AHR; TOX; TRIP6; MAFB; MTF2; BASP1