Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID25447 Unc-1215 GSE70138 ASC Human 24h 1.11uM EID0068
Types Number Response transcription factors
Up-regulation 559 SUV39H1; MNAT1; CDK9; NRF1; TAF5; SNIP1; DLX4; ERBB4; CREBZF; NR5A2; ZNF304; ZNF292; TGS1; ARNT; ZNF134; NR1H3; PEX2; TBL1XR1; ZBTB6; ZNF184; PSMC3; ID4; TTF1; IKZF5; INSM1; HDAC5; ZNF8; SMAD4; ZMYND11; RFX2; PQBP1; ZNF165; CSDC2; WDHD1; CBX7; ZNF22; NR2C2; ZNF211; ARID3B; EED; BCOR; KDM5A; BLM; ZNF764; ZSCAN16; LIMD1; HOXC5; FOXA2; WWP1; ZNF35; ZNF551; NSD1; ABT1; GFI1; ZNF324B; FOXH1; GATA6; ZNF419; TAF9B; TOPORS; ZNF587; ZBTB20; MYB; ZNF24; JUNB; ASCL3; HOXC13; RBM14; PRDM10; ZSCAN31; FHL5; ZBTB39; ZNF350; HLF; FLI1; ZBTB44; SCAI; TSC22D2; MYOG; TSHZ2; HSF2; ELF2; NEUROD1; NHLH1; BRIP1; ZNF324; ZNF639; ZNF667; E2F1; ZNF770; ZNF286A; APBB1; ELK1; TRIP11; CEBPZ; SOX17; ASH1L; EPAS1; DACH1; NKX2-2; NPAT; SAFB; HIPK2; ZNF215; ZNF175; SP4; ZNF493; PML; ZNF701; OLIG2; VDR; ZKSCAN7; RUNX1; ZNF227; MYRF; NKX2-8; HLX; CBX2; MBD1; THRB; TFDP3; SUPT3H; TFEC; PIAS4; TADA2A; ZNF710; TFDP2; SP1; ZNF669; CHD7; ARHGAP35; RSF1; CENPB; TOX; MAK; MED31; MYT1; PIAS1; KLF15; NKX2-1; OVOL2; EVX1; TLX1; ZNF586; ZSCAN2; KLF13; ZNF343; SP2; ORC2; POU3F1; MED27; ZNF142; TOB1; MNX1; KAT7; MYCL; ZNF236; ZIM2; ZNF696; HMGB3; MLXIPL; AATF; SSX7; ZNF329; RBBP5; ZNF695; RARA; ZNF197; NFYB; EMX2; SSBP3; WHSC1L1; EHMT1; ZNF771; FOXL1; ZNF225; TFE3; RBBP8; TAF12; LHX2; ZBTB48; NR1I3; RBL1; NR1I2; HNF4A; TTF2; ZNF75D; ZNF287; EMX1; GCM1; PAX6; CIR1; HIPK3; ZKSCAN8; ONECUT2; NRBF2; ZNF41; NR1D2; YEATS4; ETV3; CCNT1; ZNF14; ZBTB7B; AIRE; RFX7; HNF4G; IRF2; HOXC11; OVOL1; HNF1B; SIX3; ZNF235; PRDM8; ZNF507; UBE2B; SMAD7; NEUROD2; CXXC1; MEF2D; SMARCA1; LZTS1; ONECUT1; ZFX; PRDM13; RXRA; MAPK8IP1; PSMC3IP; BARX2; SUV39H2; ETV2; ZNF614; MED20; HOXC4; PGR; EGR4; PRDM4; FOXD3; SOX3; ZNF223; POU3F3; ING4; SOHLH2; ZNF711; HOXA7; DOT1L; HABP4; ZNF263; RBL2; E2F8; ZNF155; LHX6; RFX3; IRF6; ARRB1; ADNP2; EBF2; EP400; HEYL; NEUROD4; PRDM5; ZNF506; MED14; GABPA; ELF4; TAF1A; WNT4; NR6A1; ZBTB25; SSX3; SIX6; MYF6; ZNF613; VPS72; WDR77; KLF12; ZNF135; PKNOX1; GATA4; NFATC4; ZNF571; PAWR; THAP3; CIITA; ZNF556; ZNF552; ZNF257; HEY2; ZNF550; TERF1; TAF6L; TRIM33; ZXDC; MBD4; TOX3; NEUROG1; ZBTB3; CAMTA1; ZNF180; HIVEP1; ZNF391; ELK4; ADRB2; ZIC3; ZNF510; RBPJL; HOXA4; FOXN3; FOXG1; NR3C1; PREB; ZNF813; ZBTB43; AFF3; SERTAD2; ZNF112; POU3F2; MXD4; PAX1; KLF9; SOX5; NANOG; FOXL2; PBX3; UTF1; ZNF446; ZNF254; LBX1; MEF2A; KLF5; ZNF480; BRF2; LMCD1; MNDA; ZNF219; HOXA6; LHX3; CASZ1; EZH1; SPIB; ZXDB; ASCL2; FOXB1; MLLT1; MAP3K10; ZNF492; HOXB8; TEF; ZNF157; NCOA2; MXD1; ZNF224; HIVEP2; KAT8; SFMBT1; ZNF549; ZNF34; KMT2A; ALX4; FOXC2; CREM; ZNF749; POU4F3; POU4F2; ZMIZ2; THRAP3; ZEB2; ESRRB; RARG; AGO2; ZNF682; GBX1; ZNF214; CBL; CHAF1B; THAP9; URI1; HMG20A; RORB; ZNF345; PRDM16; ZNF536; ZNF234; RORC; TBL1Y; POU3F4; HIPK1; ZNF471; ZNF124; FOXD2; HOXD3; ZNF440; TLX3; POU6F1; MYEF2; TBX2; HR; GRIP1; ZNF778; VEZF1; LMO1; ING1; PAX7; HOXC8; GSC2; POU1F1; ZNF816; NFATC1; ZNF460; THAP10; POU2F3; BCLAF1; PRDM2; RFX1; ZNF189; ZNF221; THRA; ZNF154; SOX21; ZNF780B; BRWD1; ILF2; SETD2; NLK; EGR2; WHSC1; NFATC3; HOXA2; ZNF222; ZNF544; IL16; ETS1; VHL; PITX2; ZNF442; TAF4B; SAP130; NRL; ZNF177; ZNF81; SKIL; CHD2; FOXK2; HDAC11; CAMTA2; PLAGL2; TFAP2B; DLX6; SOX12; PRDM9; NFRKB; ZNF80; NEUROG2; ZNF407; BCL11A; PLAG1; CDX4; ARID4A; ENO1; ZNF131; MTA2; SSX1; MECOM; EDF1; BNC1; ZNF516; SRY; ETS2; UBE2L3; TULP4; ZNF532; TBX21; ZFP36L2; ACTL6B; MYT1L; SHOX; SMAD6; TBX1; PRDM14; BRCA2; HDAC4; ZNF334; PRRX1; PRKDC; GCM2; PKNOX2; E2F3; SOX10; KDM5D; TCF21; PIAS2; ZNF302; PHIP; GCFC2; ZNF10; ZNF394; ZNF239; AFF1; ZNF675; ZNF107; TP63; PRDM1; SMARCA2; ZNF443; IRF4; ZNF768; ERF; PAX4; CTNNB1; PRDM12; DBP; ZNF674; FOXM1; CRY1; ZNF248; MDM4; BBX; CRYM; HOXA5; IKZF3; ZNF665; IRF9; GATA3; VGLL1; CDK2; JAK2; MYBL2; NCOA1; BATF; TEAD4; ASCL1; HIC2; ZNF589; MYBL1; SMAD5; INSR; ST18; WT1; NR1H2; GRHL2; ZNF331; FOXJ1; ANKRD1; STAT4; GMNN; ZSCAN18; DLX2; CEBPD; LIN28A; TCF4; BHLHE41; IRX5; ID1; DLX5; ZHX2; CBFA2T3; BASP1; ID3; ZNF423; ESR1
Down-regulation 173 GTF2A2; CDK7; MNT; ATF1; TRIM22; CBFB; SP100; YBX1; HHEX; TBL1X; BTF3; NR2F6; SP140L; PDLIM1; FOXO1; SLC2A4RG; SMAD1; PITX1; TLE1; DDIT3; CBX3; STAT1; LOXL2; EYA1; RNF10; CNOT2; POU2AF1; C1QBP; TAF9; RBM39; ZMYND8; PHF20; APEX1; ABL1; CCNA2; RCOR3; SP110; HMGN3; EYA2; HSBP1; CHD9; C1D; RAN; DNMT1; CARM1; RBFOX2; ARL2BP; CCNC; TCF3; MAZ; CRK; MITF; TLE4; HOXB6; CNBP; PATZ1; TCEA1; SSBP2; FOSB; IRF7; PCGF2; ZNF23; TAF4; MDM2; SMARCA4; GTF3A; SCMH1; MAGED1; HMG20B; IRF8; SNAI2; BMI1; HOXA10; CITED1; DEAF1; TGFB1I1; LYL1; THAP4; JUND; HMGXB4; ATF4; ZNF512B; BRD4; NR2F2; ZFP64; GTF2IRD1; ADNP; HLTF; ZZZ3; GLI3; ARID1A; MLXIP; THAP11; FLNA; ATF5; MAX; RNF138; SMARCD3; PSIP1; TRIP6; NR2F1; ITGB3BP; ERBB2; HIRA; PA2G4; BANP; AR; YEATS2; FOXF1; PFDN5; IFI16; YBX3; MTDH; ZFP36L1; NFE2L2; NCOA4; FHL2; AES; MED24; MED16; HOXA11; CHD3; MAFB; MYCN; BIRC2; NR2C1; FOXJ3; MEIS2; GATAD2A; CHD8; PAX5; RFXANK; SALL1; MAF; SIX2; PBX1; DNAJC1; ZNF91; SP140; ELF1; NEDD8; TDP2; TGFB1; MLX; NFE2; REL; MED21; TULP3; RREB1; WWTR1; DNAJC2; ELK3; ZNF146; HMGA1; CD3D; EHF; ATF3; HEY1; FOXC1; ARNTL2; KLF4; ZNF12; TFAP2C; CITED2; MXI1; PTTG1; JUP; TWIST1; MTF2; TCFL5; CREB1; RELB; IKZF1