Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID25411 Iox2 GSE70138 ASC Human 24h 10uM EID0068
Types Number Response transcription factors
Up-regulation 64 MNAT1; NUP62; KDM5A; ZNF24; CASZ1; MAX; EED; KAT2B; KAT2A; ADNP2; SRF; CBX6; ZNF267; SAP30; REPIN1; TGIF1; SIAH2; HIC2; RING1; FOXJ2; TP63; TFAP2C; ZNF282; NFIC; MED15; ZNF768; RBBP7; TRIM16; THAP7; IRX4; CNOT2; TCF12; EMX2; NCOR2; ZBTB16; ELF4; RBBP8; ARNTL2; TRIP6; IRF8; LOXL2; TOX; WT1; CARHSP1; ATN1; SMARCD3; CTNNB1; STAT6; GATA6; FOXC1; DLX5; MAF; EHF; IRF6; CEBPD; TGFB1I1; HLF; TRIM29; ZEB1; TRPS1; DAXX; KLF4; MAFB; HEY1
Down-regulation 114 CITED1; STAT1; NHLH2; PPARGC1A; NONO; ABL1; SOX11; INSM1; ECD; ZNF529; POU2F1; JUND; PFDN5; NR2F6; ZNF544; PROX1; NR4A3; SMARCA1; NR4A2; NR1I2; FOXO3; CAMTA1; RBPMS; ARID1A; FOSL1; CHD1; NKX2-1; CREB5; EDF1; NR2C2; HAND1; RERE; ZNF93; ZNF83; CHD9; ZNF571; CREG1; ZNF117; ZKSCAN7; ATF5; ZNF432; ACTL6B; ZNF606; ZNF492; CLOCK; ZNF675; POU4F1; CCNT1; ZKSCAN8; ZNF573; RFX7; HMGB1; FLI1; ERG; ZNF682; ZNF331; MDM4; MYT1; TCEB2; TMF1; NR1D2; ZFP69B; TEAD1; RSF1; YBX1; ZNF10; BRIP1; RBPJ; KDM5D; ZNF254; EPAS1; SMAD7; ZNF493; SFPQ; HDAC9; BAZ2A; CRYM; CHD7; CSDE1; BRCA2; ETS1; NLK; TSC22D2; NEUROD1; ZBTB18; IKZF3; SP110; L3MBTL1; MSX1; DACH1; TAF9B; TOX3; HOXC10; SIX1; ZNF195; ZNF43; TAF4B; CD3D; HOXD1; LITAF; BCLAF1; DLX2; ST18; TBL1X; FOXA1; PLAGL1; PBX3; YBX3; MYT1L; TXNIP; E2F2; HOXC6; CREB1; ID1